Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Chandrasekaran, E.V.; Savila, M.; Nixon, D.; Mendicino, J.
    Purification and properties of alpha-D-mannose:beta-1,2-N-acetylglucosaminyl-transferases and alpha-D-mannosidases from human adenocarcinoma (1984), Cancer Res., 44, 4059-4068.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.2.1.114 0.2
-
 D-Manalpha(1-6)(Manalpha(1-3))Manalpha(1-6)(GlcNAcbeta(1-2)Manalpha(1-3))Manbeta(1-4)GlcNAcbeta(1-4)GlcNAc-Asn i.e. glycopeptide III Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.2.1.113 membrane
-
 Homo sapiens 16020
-
3.2.1.113 microsome
-
 Homo sapiens
-
-
3.2.1.114 microsome
-
 Homo sapiens
-
-

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.113 Homo sapiens
-
-
-
3.2.1.114 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.2.1.113 partial Homo sapiens
3.2.1.114 partial Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.2.1.113 colonic adenocarcinoma cell
-
 Homo sapiens
-
3.2.1.113 hepatoma cell
-
 Homo sapiens
-
3.2.1.114 colonic adenocarcinoma cell
-
 Homo sapiens
-
3.2.1.114 hepatoma cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.113 Manalpha(1-2)Manalpha(1-6)(Manalpha(1-2)Manalpha(1-3))Manalpha(1-6)Manalpha(1-2)Manalpha(1-2)Manalpha(1-3)Manbeta(1-4)GlcNAcbeta(1-4)GlcNAc + H2O i.e. (Man)9(GlcNAc)2 Homo sapiens (Man)6(GlcNAc)2 + D-mannose
-
 ?
3.2.1.113 Manalpha(1-6)(Manalpha(1-3))Manalpha(1-6)(Manalpha(1-2)Manalpha(1-3))Manbeta(1-4)GlcNAcbeta(1-4)GlcNAc + H2O i.e. GPIV Homo sapiens (Man)5(GlcNAc)2-Asn + D-mannose major product formed, 3.5 mol mannose/mol GP IV per h ?
3.2.1.113 Manalpha(1-6)(Manalpha(1-3))Manalpha(1-6)(Manalpha(1-2)Manalpha(1-3))Manbeta(1-4)GlcNAcbeta(1-4)GlcNAc + H2O i.e. GPIV Homo sapiens (Man)5(GlcNAc)2-Asn + D-mannose i.e. GPI ?
3.2.1.113 additional information no substrate: GP III Homo sapiens ?
-
 ?
3.2.1.113 additional information no substrate: (Man)5(GlcNAc)2-Asn (i.e. GPI) Homo sapiens ?
-
 ?
3.2.1.114 D-Manalpha(1-6)(Manalpha(1-3))Manalpha(1-6)(GlcNAcbeta(1-2)Manalpha(1-3))Manbeta(1-4)GlcNAcbeta(1-4)GlcNAc-Asn + H2O i.e. glycopeptide III, derived from ovalbumin, no hydrolysis of the innermost alpha-1,6-linked or the alpha-1,2-linked mannose Homo sapiens D-Manalpha(1-6)(GlcNAcbeta(1-2)Manalpha(1-3))Manbeta(1-4)GlcNAcbeta(1-4)GlcNAc-Asn + alpha-D-mannose i.e. glycopeptide II ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.2.1.113 37
-
 assay at Homo sapiens
3.2.1.114 37
-
 assay at Homo sapiens