Literature summary extracted from

Lee, J.Y.; Lee, H.J.; Kim, M.R.; Myung, P.K.; Sok, D.E.
Regulation of brain glycosylphosphatidylinositol-specific phospholipase D by natural amphiphiles (1999), Neurochem. Res., 24, 1577-1583.

Activating Compound

EC Number	Activating Compound	Comment	Organism	Structure
3.1.4.50	monoacylglycerol	stimulates in a size-dependent manner, maximal enhancement with monodecanoylglycerol	Bos taurus
3.1.4.50	monodecanoylglycerol	-	Bos taurus

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
3.1.4.50	lysophosphatidylcholine	50% inhibition at 0.05 mM	Bos taurus
3.1.4.50	phosphatidic acid	50% inhibition at 0.1 mM	Bos taurus

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.1.4.50	Bos taurus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.1.4.50	brain	-	Bos taurus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.1.4.50	Zn2+-glycerophosphocholine cholinephosphodiesterase, amphiphilic form + H2O	-	Bos taurus	Zn2+-glycerophosphocholine cholinephosphodiesterase, hydrophilic form	-	?

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Release 2023.1 (January 2023)