BRENDA - Enzyme Database

Regulation of brain glycosylphosphatidylinositol-specific phospholipase D by natural amphiphiles

Lee, J.Y.; Lee, H.J.; Kim, M.R.; Myung, P.K.; Sok, D.E.; Neurochem. Res. 24, 1577-1583 (1999)

Data extracted from this reference:

Activating Compound
EC Number
Activating Compound
Commentary
Organism
Structure
3.1.4.50
monoacylglycerol
stimulates in a size-dependent manner, maximal enhancement with monodecanoylglycerol
Bos taurus
3.1.4.50
monodecanoylglycerol
-
Bos taurus
Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
3.1.4.50
lysophosphatidylcholine
50% inhibition at 0.05 mM
Bos taurus
3.1.4.50
phosphatidic acid
50% inhibition at 0.1 mM
Bos taurus
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
3.1.4.50
Bos taurus
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
3.1.4.50
brain
-
Bos taurus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.1.4.50
Zn2+-glycerophosphocholine cholinephosphodiesterase, amphiphilic form + H2O
-
646483
Bos taurus
Zn2+-glycerophosphocholine cholinephosphodiesterase, hydrophilic form
-
646483
Bos taurus
?
Activating Compound (protein specific)
EC Number
Activating Compound
Commentary
Organism
Structure
3.1.4.50
monoacylglycerol
stimulates in a size-dependent manner, maximal enhancement with monodecanoylglycerol
Bos taurus
3.1.4.50
monodecanoylglycerol
-
Bos taurus
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
3.1.4.50
lysophosphatidylcholine
50% inhibition at 0.05 mM
Bos taurus
3.1.4.50
phosphatidic acid
50% inhibition at 0.1 mM
Bos taurus
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
3.1.4.50
brain
-
Bos taurus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.1.4.50
Zn2+-glycerophosphocholine cholinephosphodiesterase, amphiphilic form + H2O
-
646483
Bos taurus
Zn2+-glycerophosphocholine cholinephosphodiesterase, hydrophilic form
-
646483
Bos taurus
?