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Literature summary extracted from

  • Larson, T.J.; Ehrmann, M.; Boos, W.
    Periplasmic glycerophosphodiester phosphodiesterase of Escherichia coli, a new enzyme of the glp regulon (1983), J. Biol. Chem., 258, 5428-5432.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.4.46 EDTA
-
Escherichia coli
3.1.4.46 Mg2+ 4 mM Escherichia coli
3.1.4.46 Mn2+ 4 mM Escherichia coli

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.4.46 0.2
-
glycerophosphocholine 25°C, pH 9.0 Escherichia coli
3.1.4.46 0.2
-
glycerophosphoethanolamine 25°C, pH 9.0 Escherichia coli
3.1.4.46 0.2
-
glycerophosphoglycerol 25°C, pH 9.0 Escherichia coli
3.1.4.46 0.6
-
bis(glycerophospho)glycerol 25°C, pH 9.0 Escherichia coli

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.4.46 microsome
-
Escherichia coli
-
-
3.1.4.46 periplasm
-
Escherichia coli
-
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.4.46 Ca2+ 4 mM, stimulates Escherichia coli

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.4.46 glycerophosphocholine + H2O Escherichia coli
-
sn-glycerol 3-phosphate + choline
-
?

Organism

EC Number Organism UniProt Comment Textmining
3.1.4.46 Escherichia coli
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.4.46 bis(glycerophospho)glycerol + H2O
-
Escherichia coli sn-gycerol 3-phosphate + ?
-
?
3.1.4.46 cyclic sn-2,3-phosphoglycerol + H2O
-
Escherichia coli ?
-
?
3.1.4.46 glycerophosphocholine + H2O
-
Escherichia coli sn-glycerol 3-phosphate + choline
-
?
3.1.4.46 glycerophosphoethanolamine + H2O
-
Escherichia coli sn-glycerol 3-phosphate + ethanolamine
-
?
3.1.4.46 glycerophosphoglycerol + H2O
-
Escherichia coli sn-glycerol 3-phosphate + glycerol
-
?
3.1.4.46 additional information not: bis(4-nitrophenyl)phosphate Escherichia coli ?
-
?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.4.46 9
-
-
Escherichia coli