Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Howell, S.; Barnaby, R.J.; Rowe, T.; Ragan, C.I.; Gee, N.S.
    Evidence for at least four different inositol bisphosphatases in bovine brain (1989), Eur. J. Biochem., 183, 169-172.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.3.57 5,5'-dithiobis(nitrobenzoic acid)
-
 Bos taurus
3.1.3.57 Li+
-
 Bos taurus
3.1.3.66 (NH4)2SO4
-
 Bos taurus
3.1.3.66 5,5'-dithiobis(nitrobenzoic acid)
-
 Bos taurus
3.1.3.66 KCl moderate salt concentrations Bos taurus
3.1.3.66 KNO3
-
 Bos taurus
3.1.3.66 additional information no inhibition by Li+ Bos taurus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.3.57 cytosol
-
 Bos taurus 5829
-
3.1.3.66 cytosol
-
 Bos taurus 5829
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.3.57 Mg2+ requirement Bos taurus
3.1.3.66 additional information no Mg2+ requirement Bos taurus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.3.57 38000
-
 gel filtration Bos taurus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.3.57 D-myo-inositol 1,4-bisphosphate + H2O Bos taurus
-
 D-myo-inositol 4-phosphate + phosphate
-
 ?
3.1.3.66 D-myo-inositol 3,4-bisphosphate + H2O Bos taurus
-
 D-myo-inositol 4-phosphate + phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.57 Bos taurus
-
-
-
3.1.3.66 Bos taurus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.3.57 brain
-
 Bos taurus
-
3.1.3.66 brain
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.3.57 D-myo-inositol 1,4-bisphosphate + H2O
-
 Bos taurus D-myo-inositol 4-phosphate + phosphate
-
 ?
3.1.3.66 D-myo-inositol 3,4-bisphosphate + H2O
-
 Bos taurus D-myo-inositol 4-phosphate + phosphate
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.3.66 7.6
-
-
 Bos taurus