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Literature summary extracted from

  • Lynch, B.J.; Challiss, R.A.J.; Chilvers, E.R.
    Characterisation and Ca(2+)-dependency of the soluble and particulate Ins(1,4,5)P3 5-phosphatase in bovine tracheal smooth muscle (1994), Biochem. Soc. Trans., 22, 314S.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.3.56 Ca2+ above 0.001 mM Bos taurus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.3.56 0.018
-
 D-myo-inositol 1,4,5-trisphosphate particulate enzyme Bos taurus
3.1.3.56 0.019
-
 D-myo-inositol 1,4,5-trisphosphate soluble enzyme Bos taurus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.3.56 membrane 5 times higher Vmax than soluble enzyme Bos taurus 16020
-
3.1.3.56 soluble
-
 Bos taurus
-
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.3.56 Ca2+ moderate inhibition Bos taurus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.3.56 D-myo-inositol 1,4,5-trisphosphate + H2O Bos taurus regulation of intracellular Ca2+ level by degradation of intracellular Ca2+ releasing second messenger D-myo-inositol 1,4,5-trisphosphate D-myo-inositol 1,4-bisphosphate + phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.56 Bos taurus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.3.56 muscle tracheal smooth muscle Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.3.56 D-myo-inositol 1,4,5-trisphosphate + H2O
-
 Bos taurus D-myo-inositol 1,4-bisphosphate + phosphate
-
 ?
3.1.3.56 D-myo-inositol 1,4,5-trisphosphate + H2O regulation of intracellular Ca2+ level by degradation of intracellular Ca2+ releasing second messenger D-myo-inositol 1,4,5-trisphosphate Bos taurus D-myo-inositol 1,4-bisphosphate + phosphate
-
 ?