Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Fowler, C.J.; Brännström, G.
    Kinetic and inhibitor profiles of soluble and particulate inositol 1,4-5-trisphosphate 5-phosphatase from GH3 and IMR-32 cells (1990), Biochem. J., 271, 735-742.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.3.56 2,3-bisphosphoglycerate
-
 Homo sapiens
3.1.3.56 2,3-bisphosphoglycerate
-
 Rattus norvegicus
3.1.3.56 CdCl2
-
 Homo sapiens
3.1.3.56 CdCl2
-
 Rattus norvegicus
3.1.3.56 D-fructose 1,6-bisphosphate
-
 Homo sapiens
3.1.3.56 D-fructose 1,6-bisphosphate
-
 Rattus norvegicus
3.1.3.56 D-fructose 2,6-bisphosphate
-
 Homo sapiens
3.1.3.56 D-fructose 2,6-bisphosphate
-
 Rattus norvegicus
3.1.3.56 D-glucose 6-phosphate
-
 Homo sapiens
3.1.3.56 D-glucose 6-phosphate
-
 Rattus norvegicus
3.1.3.56 Inositol 1,3,4,5-tetrakisphosphate
-
 Homo sapiens
3.1.3.56 Inositol 1,3,4,5-tetrakisphosphate
-
 Rattus norvegicus
3.1.3.56 p-hydroxymercuribenzoate
-
 Homo sapiens
3.1.3.56 p-hydroxymercuribenzoate
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.3.56 membrane major part of activity is membrane bound Homo sapiens 16020
-
3.1.3.56 membrane major part of activity is membrane bound Rattus norvegicus 16020
-
3.1.3.56 soluble two different soluble enzymes, type I and type II Homo sapiens
-
-
3.1.3.56 soluble two different soluble enzymes, type I and type II Rattus norvegicus
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.3.56 D-myo-inositol 1,4,5-trisphosphate + H2O Homo sapiens regulation of intracellular Ca2+ level by degradation of intracellular Ca2+ releasing second messenger D-myo-inositol 1,4,5-trisphosphate D-myo-inositol 1,4-bisphosphate + phosphate
-
 ?
3.1.3.56 D-myo-inositol 1,4,5-trisphosphate + H2O Rattus norvegicus regulation of intracellular Ca2+ level by degradation of intracellular Ca2+ releasing second messenger D-myo-inositol 1,4,5-trisphosphate D-myo-inositol 1,4-bisphosphate + phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.56 Homo sapiens
-
 IMR-32 neuroblastoma cells
-
3.1.3.56 Rattus norvegicus
-
 GH3 pituitary cells
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.3.56 cerebral cortex
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.3.56 D-myo-inositol 1,4,5-trisphosphate + H2O
-
 Homo sapiens D-myo-inositol 1,4-bisphosphate + phosphate
-
 ?
3.1.3.56 D-myo-inositol 1,4,5-trisphosphate + H2O
-
 Rattus norvegicus D-myo-inositol 1,4-bisphosphate + phosphate
-
 ?
3.1.3.56 D-myo-inositol 1,4,5-trisphosphate + H2O regulation of intracellular Ca2+ level by degradation of intracellular Ca2+ releasing second messenger D-myo-inositol 1,4,5-trisphosphate Homo sapiens D-myo-inositol 1,4-bisphosphate + phosphate
-
 ?
3.1.3.56 D-myo-inositol 1,4,5-trisphosphate + H2O regulation of intracellular Ca2+ level by degradation of intracellular Ca2+ releasing second messenger D-myo-inositol 1,4,5-trisphosphate Rattus norvegicus D-myo-inositol 1,4-bisphosphate + phosphate
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.3.56 7
-
-
 Homo sapiens
3.1.3.56 7
-
-
 Rattus norvegicus

pH Range

EC Number pH Minimum pH Maximum Comment Organism
3.1.3.56 6.25 8.25
-
 Homo sapiens
3.1.3.56 6.25 8.25
-
 Rattus norvegicus