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Literature summary extracted from

  • Cheung, J.I.; Wang, Y.R.; Lin, A.
    Substrate specificity of monomeric and dimeric alpha-sarcin (1996), FEBS Lett., 386, 60-64.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.6.1.23 Sodium dodecyl sulfate reversible inhibition of ribonuclease activity, irreversible inhibition of deoxyribonuclease activity Aspergillus giganteus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.6.1.23 rRNA + H2O Aspergillus giganteus
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.6.1.23 Aspergillus giganteus
-
 filamentous fungus, mold
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.6.1.23 28 S rRNA + H2O mini-stem-loop RNA Aspergillus giganteus alpha-fragment from the 3' end of 28S rRNA
-
 ?
4.6.1.23 additional information major type II ribotoxin Aspergillus giganteus ?
-
 ?
4.6.1.23 RNA + H2O
-
 Aspergillus giganteus ?
-
 ?
4.6.1.23 rRNA + H2O
-
 Aspergillus giganteus ?
-
 ?
4.6.1.23 supercoiled double-stranded DNA + H2O
-
 Aspergillus giganteus nicked circular conformation of DNA
-
 ?

Subunits

EC Number Subunits Comment Organism
4.6.1.23 dimer dimeric form fails to inactivate ribosomes as well as to hydrolyze mini-stem-loop RNA, but is an effective ribonuclease in situ Aspergillus giganteus
4.6.1.23 monomer
-
 Aspergillus giganteus