EC Number | Cloned (Comment) | Organism |
---|---|---|
3.4.19.12 | UBPY, DNA sequence determination and analysis, expression of gene fragment, residues 9-188, fused to GST in a bacterial expression system | Homo sapiens |
3.4.19.12 | UBPY, expression of wild-type enzyme and mutant D786A in NIH 3T3 cells | Homo sapiens |
EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
3.4.19.12 | C786A | site-directed mutagenesis, no activity | Homo sapiens |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.4.19.12 | N-ethylmaleimide | UBPY | Homo sapiens |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
3.4.19.12 | 130000 | - |
x * 130000, SDS-PAGE | Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.19.12 | additional information | Homo sapiens | enzyme inhibits cell proliferation | ? | - |
? | |
3.4.19.12 | additional information | Homo sapiens | enzyme regulation | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.19.12 | Homo sapiens | P40818 | UBPY | - |
EC Number | Purification (Comment) | Organism |
---|---|---|
3.4.19.12 | recombinant truncated GST-fusion protein of UBPY | Homo sapiens |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.4.19.12 | C33A cell | human cervical carcinoma cell line | Homo sapiens | - |
3.4.19.12 | fibroblast | accumulated upon growth stimulation of starved human fibroblasts | Homo sapiens | - |
3.4.19.12 | U2-OS cell | human osteosarcoma cell line | Homo sapiens | - |
3.4.19.12 | WI-38 cell | human fibroblast cell line | Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.19.12 | branched polyubiquitin + H2O | isopeptide-linked ubiquitin chains | Homo sapiens | ubiquitin | - |
? | |
3.4.19.12 | additional information | enzyme inhibits cell proliferation | Homo sapiens | ? | - |
? | |
3.4.19.12 | additional information | enzyme regulation | Homo sapiens | ? | - |
? | |
3.4.19.12 | polyubiquitin + H2O | linear chains | Homo sapiens | ubiquitin | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
3.4.19.12 | ? | x * 130000, SDS-PAGE | Homo sapiens |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.4.19.12 | UBPY | - |
Homo sapiens |