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Literature summary extracted from
- Molecular cloning, sequencing, and expression of human myocardial fatty acid ethyl ester synthase-III cDNA (1991), J. Biol. Chem., 266, 16774-16777.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 3.1.1.67 | cDNA encoding FAEES-III is cloned from heart, sequenced and expressed in MCF-7 and COS-7 cells, 210 amino acid sequence | Homo sapiens |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.1.1.67 | 23307 | - |
x * 23307, FAEES-III, calculated from the amino acid sequence | Homo sapiens |
| 3.1.1.67 | 24000 | - |
x * 24000, FAEES-III, SDS-PAGE | Homo sapiens |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.1.67 | fatty acid + ethanol | Homo sapiens | nonoxidative ethanol metabolism | fatty acyl ethyl ester + H2O | - |
? |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.1.67 | Homo sapiens | - |
FAEES-III | - |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.1.1.67 | heart | myocardium | Homo sapiens | - |
| 3.1.1.67 | heart | FAEES-III mRNA expression | Homo sapiens | - |
| 3.1.1.67 | liver | FAEES-III mRNA expression | Homo sapiens | - |
| 3.1.1.67 | myocardium | FAEES-III, one of 3 human myocardial forms | Homo sapiens | - |
| 3.1.1.67 | placenta | FAEES-III mRNA expression | Homo sapiens | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.1.67 | fatty acid + ethanol | - |
Homo sapiens | fatty acyl ethyl ester + H2O | - |
? | |
| 3.1.1.67 | fatty acid + ethanol | nonoxidative ethanol metabolism | Homo sapiens | fatty acyl ethyl ester + H2O | - |
? | |
| 3.1.1.67 | additional information | recombinant myocardial FAEES-III has also significant GST activity | Homo sapiens | ? | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 3.1.1.67 | ? | x * 23307, FAEES-III, calculated from the amino acid sequence | Homo sapiens |
| 3.1.1.67 | ? | x * 24000, FAEES-III, SDS-PAGE | Homo sapiens |
pI Value
| EC Number | Organism | Comment | pI Value Maximum | pI Value |
|---|---|---|---|---|
| 3.1.1.67 | Homo sapiens | myocardial FAEES-III | - |
4.9 |
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