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Literature summary extracted from

  • Eisenman, R.A.; Balasubramanian, A.S.; Marx, W.
    3-Phosphoadenylylsulfate:N-desulfoheparin sulfotransferase associated with a postmicrosomal particulate mastocytoma fraction (1967), Arch. Biochem. Biophys., 119, 387-397.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.8.2.8 Cu2+
-
 Mus musculus
2.8.2.8 PCMB
-
 Mus musculus
2.8.2.8 phenylmercuric acetate
-
 Mus musculus
2.8.2.8 Zn2+
-
 Mus musculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.8.2.8 additional information associated with postmicrosomal fraction Mus musculus
-
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.8.2.8 Mg2+ activates at 10 mM Mus musculus
2.8.2.8 additional information greatest activity in presence of sodium phosphate buffer, in imidazole-HCl reaction rate is lower Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
2.8.2.8 Mus musculus
-
 Furth mouse
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.8.2.8
-
 Mus musculus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.8.2.8 mastocytoma cell
-
 Mus musculus
-

Storage Stability

EC Number Storage Stability Organism
2.8.2.8 -18°C, stable for at least 4 months Mus musculus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.8.2.8 3'-phosphoadenylylsulfate + chondroitin 4-sulfate weak activity Mus musculus ?
-
 ?
2.8.2.8 3'-phosphoadenylylsulfate + dermatan sulfate weak activity Mus musculus ?
-
 ?
2.8.2.8 3'-phosphoadenylylsulfate + heparan sulfate
-
 Mus musculus adenosine 3',5'-bisphosphate + N-sulfoheparan sulfate
-
 ?
2.8.2.8 3'-phosphoadenylylsulfate + N-desulfated heparin
-
 Mus musculus ?
-
 ?
2.8.2.8 additional information p-nitrophenol is no acceptor Mus musculus ?
-
 ?
2.8.2.8 additional information heparin is no acceptor Mus musculus ?
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.8.2.8 37
-
 assay at Mus musculus

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
2.8.2.8 40
-
 2 min, no effect Mus musculus
2.8.2.8 55
-
-
 Mus musculus
2.8.2.8 70
-
-
 Mus musculus
2.8.2.8 85
-
 2 min, complete loss of activity Mus musculus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.8.2.8 6.7 7.2
-
 Mus musculus