Literature summary extracted from

Qian, Y.; Song, W.C.
Correlation between PAP-dependent steroid binding activity and substrate specificity of mouse and human estrogen sulfotransferases (1999), J. Steroid Biochem. Mol. Biol., 71, 123-131.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
2.8.2.4	-	Homo sapiens
2.8.2.4	EST cDNA cloned and expressed as fusion protein in Escherichia coli using pGEX-4T-3 and in CHO cells using eukaryotic expression vector pCDNA3	Mus musculus

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
2.8.2.4	cytosol	-	Mus musculus	5829	-
2.8.2.4	cytosol	-	Homo sapiens	5829	-

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
2.8.2.4	3'-phosphoadenylylsulfate + estradiol	Mus musculus	-	adenosine 3',5'-bisphosphate + estradiol 3-sulfate	-	r
2.8.2.4	3'-phosphoadenylylsulfate + estradiol	Homo sapiens	-	adenosine 3',5'-bisphosphate + estradiol 3-sulfate	-	r

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.8.2.4	Homo sapiens	-	human	-
2.8.2.4	Mus musculus	-	mouse	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.8.2.4	3'-phosphoadenylylsulfate + dehydroepiandrosterone	-	Mus musculus	adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate	-	r
2.8.2.4	3'-phosphoadenylylsulfate + dehydroepiandrosterone	-	Homo sapiens	adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate	-	r
2.8.2.4	3'-phosphoadenylylsulfate + estradiol	-	Mus musculus	adenosine 3',5'-bisphosphate + estradiol 3-sulfate	-	r
2.8.2.4	3'-phosphoadenylylsulfate + estradiol	-	Homo sapiens	adenosine 3',5'-bisphosphate + estradiol 3-sulfate	-	r
2.8.2.4	3'-phosphoadenylylsulfate + pregnenolone	-	Homo sapiens	adenosine 3',5'-bisphosphate + pregnenolone 3-sulfate	-	r
2.8.2.4	additional information	dehydroepiandrosterone and pregnenolone are no substrates	Mus musculus	?	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
2.8.2.4	EST	-	Mus musculus
2.8.2.4	EST	-	Homo sapiens

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Release 2023.1 (January 2023)