Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Miki, Y.; Nakata, T.; Suzuki, T.; Darnel, A.D.; Moriya, T.; Kaneko, C.; Hidaka, K.; Shiotsu, Y.; Kusaka, H.; Sasano, H.
    Systemic distribution of steroid sulfatase and estrogen sulfotransferase in human adult and fetal tissues (2002), J. Clin. Endocrinol. Metab., 87, 5760-5768.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.6.2 estrone sulfate + H2O Homo sapiens STS converts the major circulating plasma estrogen estrone sulfate into the biologically active estrogene estrone, STS plays an important role in the in situ estrogen actions of various sex steroid-dependent tumors, peripheral STS plays a very important role in peripheral estrogen metabolism and actions in the human fetus estrone + sulfate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.8.2.2 Homo sapiens
-
 human
-
3.1.6.2 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.8.2.2 adrenal gland
-
 Homo sapiens
-
2.8.2.2 epithelium
-
 Homo sapiens
-
2.8.2.2 fetus
-
 Homo sapiens
-
2.8.2.2 kidney
-
 Homo sapiens
-
2.8.2.2 liver
-
 Homo sapiens
-
2.8.2.2 placenta
-
 Homo sapiens
-
2.8.2.2 skin
-
 Homo sapiens
-
2.8.2.2 testis
-
 Homo sapiens
-
2.8.2.2 uterus
-
 Homo sapiens
-
3.1.6.2 adrenal gland adult, relatively high STS activity Homo sapiens
-
3.1.6.2 aorta adult Homo sapiens
-
3.1.6.2 liver adult, relatively high STS activity Homo sapiens
-
3.1.6.2 lung adult Homo sapiens
-
3.1.6.2 additional information distribution of STS mRNA in human adult and fetal tissues Homo sapiens
-
3.1.6.2 placenta adult, highest STS activity Homo sapiens
-
3.1.6.2 testis adult Homo sapiens
-
3.1.6.2 thyroid gland adult Homo sapiens
-
3.1.6.2 uterus 1-3.7% of the mRNA levels of placenta, adult Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.1.6.2 additional information
-
-
 Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.6.2 estrone sulfate + H2O
-
 Homo sapiens estrone + sulfate
-
 ?
3.1.6.2 estrone sulfate + H2O STS converts the major circulating plasma estrogen estrone sulfate into the biologically active estrogene estrone, STS plays an important role in the in situ estrogen actions of various sex steroid-dependent tumors, peripheral STS plays a very important role in peripheral estrogen metabolism and actions in the human fetus Homo sapiens estrone + sulfate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.6.2 estrone sulfatase
-
 Homo sapiens
3.1.6.2 STS
-
 Homo sapiens

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.1.6.2 37
-
 assay at Homo sapiens