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Literature summary extracted from

  • Takehara, K.; Kubushiro, K.; Iwamori, Y.; Tsukazaki, K.; Nozawa, S.; Iwamori, M.
    Expression of an isoform of testis-specific estrogen sulfotransferase in murine placenta during late gestational period (2001), Arch. Biochem. Biophys., 394, 201-208.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.8.2.2 cDNA of placental EST cloned, COS-7 cells transfected with mpEST Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
2.8.2.2 Mus musculus O35400 mouse
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.8.2.2 epididymis
-
 Mus musculus
-
2.8.2.2 placenta
-
 Mus musculus
-
2.8.2.2 testis testis-specific isoform Mus musculus
-
2.8.2.2 uterus
-
 Mus musculus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.8.2.2 0.00002965
-
 substrate 4-methylumbelliferone Mus musculus
2.8.2.2 0.0000596
-
 substrate p-nitrophenol Mus musculus
2.8.2.2 0.000207
-
 substrate p-hydroxybenzoic acid methyl ester Mus musculus
2.8.2.2 0.0002474
-
 substrate p-nitrocatechol Mus musculus
2.8.2.2 0.0002614
-
 substrate estriol Mus musculus
2.8.2.2 0.0004035
-
 substrate ethynylestradiol Mus musculus
2.8.2.2 0.0004193
-
 substrate estradiol Mus musculus
2.8.2.2 0.0004737
-
 substrate estrone Mus musculus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.8.2.2 3'-phosphoadenylylsulfate + 4-methylumbelliferone
-
 Mus musculus adenosine 3',5'-bisphosphate + 4-methylumbelliferone sulfate
-
 r
2.8.2.2 3'-phosphoadenylylsulfate + estriol
-
 Mus musculus adenosine 3',5'-bisphosphate + estriol sulfate
-
 r
2.8.2.2 3'-phosphoadenylylsulfate + estrone
-
 Mus musculus adenosine 3',5'-bisphosphate + estrone sulfate
-
 r
2.8.2.2 3'-phosphoadenylylsulfate + ethynylestradiol
-
 Mus musculus adenosine 3',5'-bisphosphate + ethynylestradiol sulfate
-
 r
2.8.2.2 3'-phosphoadenylylsulfate + methyl 4-hydroxybenzoate
-
 Mus musculus adenosine 3',5'-bisphosphate + methyl 4-(sulfooxy)benzoate
-
 r
2.8.2.2 3'-phosphoadenylylsulfate + p-nitrocatechol
-
 Mus musculus adenosine 3',5'-bisphosphate + p-nitrocatechol sulfate
-
 r
2.8.2.2 3'-phosphoadenylylsulfate + p-nitrophenol
-
 Mus musculus adenosine 3',5'-bisphosphate + p-nitrophenyl sulfate
-
 r
2.8.2.2 additional information exhibits sulfotransferase activity with phenolic hydroxy groups of steroids and artificial substrates, best acceptor substrate is estrogen Mus musculus ?
-
 ?

pH Range

EC Number pH Minimum pH Maximum Comment Organism
2.8.2.2 6 10
-
 Mus musculus