Literature summary extracted from

Narasaka, T.; Moriya, T.; Endoh, M.; Suzuki, T.; Shizawa, S.; Mizokami, Y.; Matsuoka, T.; Sasano, H.
17Beta-hydroxysteroid dehydrogenase type 2 and dehydroepiandrosterone sulfotransferase in the human liver (2000), Endocr. J., 47, 697-705.

Application

EC Number	Application	Comment	Organism
2.8.2.2	medicine	diagnostic of liver diseases, in chronic hepatitis the immunopositive area of DHEA-ST is significantly increased compared to normal liver	Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
2.8.2.2	3'-phosphoadenylylsulfate + dehydroepiandrosterone	Homo sapiens	-	adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate	-	r

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.8.2.2	Homo sapiens	-	human	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.8.2.2	fetus	-	Homo sapiens	-
2.8.2.2	hepatocyte	-	Homo sapiens	-
2.8.2.2	liver	-	Homo sapiens	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.8.2.2	3'-phosphoadenylylsulfate + dehydroepiandrosterone	-	Homo sapiens	adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate	-	r
2.8.2.2	additional information	hepatic clearance and metabolism of sex steroids	Homo sapiens	?	-	?

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Release 2023.1 (January 2023)