Literature summary extracted from

Salac, M.L.B.; Santos, J.A.; Mourao, P.A.S.
Protamine increases the affinity of 3-phosphoadenosine 5-phosphosulfate toward a sulfotransferase from chicken embryo epiphyseal cartilage (1986), Biochim. Biophys. Acta, 883, 605-609.

Activating Compound

EC Number	Activating Compound	Comment	Organism	Structure
2.8.2.17	protamine	12fold activation of enzyme activity with totally desulfated chondroitin, 3fold activation with partially sulfated chondroitin	Gallus gallus

KM Value [mM]

EC Number	KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
2.8.2.17	0.0091	-	3'-phosphoadenylylsulfate	in the presence of protamine, pH 8, 37°C	Gallus gallus
2.8.2.17	0.0333	-	3'-phosphoadenylylsulfate	in the absence of protamine, pH 8, 37°C	Gallus gallus

Molecular Weight [Da]

EC Number	Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
2.8.2.17	150000	-	gel filtration	Gallus gallus

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.8.2.17	Gallus gallus	-	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
2.8.2.17	partial	Gallus gallus

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.8.2.17	epiphysis	cartilage, embryo	Gallus gallus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.8.2.17	3'-phosphoadenylylsulfate + chondroitin	-	Gallus gallus	adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate	-	?

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Release 2023.1 (January 2023)