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Literature summary extracted from

  • Sugumaran, G.; Silbert, J.E.
    Sulfation of chondroitin. Specificity, degree of sulfation, and detergent effects with 4-sulfating and 6-sulfating microsomal systems (1988), J. Biol. Chem., 263, 4673-4678.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.8.2.5 Nonidet P-40 activates at 1% Mus musculus
2.8.2.5 Triton X-100 activates at 1% Mus musculus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.8.2.5 Detergents with the exception of Triton X-100 and Nonidet P-40, inhibit sulfation in the mast cell system Mus musculus
2.8.2.17 additional information no inhibition by detergents of enzyme in chicken cartilage system Gallus gallus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.8.2.5 microsome
-
 Mus musculus
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.8.2.5 3'-phosphoadenylylsulfate + chondroitin Mus musculus
-
 adenosine 3',5'-bisphosphate + chondroitin 4'-sulfate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.8.2.5 Mus musculus
-
-
-
2.8.2.17 Gallus gallus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.8.2.5 mastocytoma cell
-
 Mus musculus
-
2.8.2.17 epiphysis cartilage, embryo Gallus gallus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.8.2.5 3'-phosphoadenylylsulfate + chondroitin
-
 Mus musculus adenosine 3',5'-bisphosphate + chondroitin 4'-sulfate
-
 ?
2.8.2.17 3'-phosphoadenylylsulfate + chondroitin
-
 Gallus gallus adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.8.2.5 37
-
 assay at Mus musculus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.8.2.5 6.5
-
 assay at Mus musculus