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Literature summary extracted from

  • Falany, C.N.; Vasquez, M.E.; Kalb, J.M.
    Purification and characterization of human liver dehydroepiandrosterone sulphotransferase (1989), Biochem. J., 260, 641-646.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.8.2.15 adenosine 3',5'-bisphosphate
-
 Homo sapiens
2.8.2.15 pregnenolone substrate inhibition Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.8.2.15 0.0016
-
 3beta-hydroxyandrost-5-ene-17-one pH 7.5, ? Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.8.2.15 cytosol
-
 Homo sapiens 5829
-
2.8.2.15 endoplasmic reticulum
-
 Homo sapiens 5783
-
2.8.2.15 Golgi apparatus
-
 Homo sapiens 5794
-
2.8.2.15 membrane
-
 Homo sapiens 16020
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.8.2.15 68000 70000 gel filtration Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.8.2.15 Homo sapiens
-
 human
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.8.2.15
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.8.2.15 liver
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.8.2.15 0.133
-
-
 Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.8.2.15 3'-phosphoadenylylsulfate + 17beta-estradiol estra-1,3,5(10)-triene-3,17alpha-diol Homo sapiens adenosine 3',5'-bisphosphate + ?
-
 r
2.8.2.15 3'-phosphoadenylylsulfate + 3alpha-hydroxy-5alpha-androstan-17-one androsterone Homo sapiens adenosine 3',5'-bisphosphate + 5alpha-androstan-17-one 3-sulfate androsterone sulfate r
2.8.2.15 3'-phosphoadenylylsulfate + 3beta-hydroxy-5alpha-androstan-17-one epiandrosterone Homo sapiens adenosine 3',5'-bisphosphate + 5alpha-androstan-17-one 3-sulfate
-
 r
2.8.2.15 3'-phosphoadenylylsulfate + androst-5-ene-3beta,17beta-diol
-
 Homo sapiens adenosine 3',5'-bisphosphate + ?
-
 r
2.8.2.15 3'-phosphoadenylylsulfate + estrone
-
 Homo sapiens adenosine 3',5'-bisphosphate + estrone sulfate estra-1,3,5(10)-trien-17-one 3-sulfate r
2.8.2.15 3'-phosphoadenylylsulfate + etiocholanone 3alpha-hydroxy-5beta-androstan-17-one Homo sapiens adenosine 3',5'-bisphosphate + etiocholanone sulfate 5beta-androstan-17-one 3-sulfate r
2.8.2.15 3'-phosphoadenylylsulfate + pregnenolone
-
 Homo sapiens adenosine 3',5'-bisphosphate + pregnenolone sulfate pregn-5-en-20-one 3-sulfate r
2.8.2.15 3'-phosphoadenylylsulfate + testosterone 17beta-hydroxyandrost-4-en-3-one Homo sapiens adenosine 3',5'-bisphosphate + testosterone sulfate androst-4-en-3-one 17-sulfate r
2.8.2.15 additional information no activity towards p-nitrophenol or dopamine Homo sapiens ?
-
 ?

Subunits

EC Number Subunits Comment Organism
2.8.2.15 dimer
-
 Homo sapiens

Synonyms

EC Number Synonyms Comment Organism
2.8.2.15 DHEA sulphotransferase
-
 Homo sapiens

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.8.2.15 0.0016
-
 adenosine 3',5'-bisphosphate pH 7.5 Homo sapiens