Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Chen, L.J.; Bolt, R.J.; Admirand, W.H.
    Enzymatic sulfation of bile salts. Partial purification and characterization of an enzyme from rat liver that catalyzes the sulfation of bile salts (1977), Biochim. Biophys. Acta, 480, 219-227.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.8.2.14 adenosine-3',5'-diphosphate
-
 Rattus norvegicus
2.8.2.14 additional information EDTA and NaF exhibits slight inhibitory effect Rattus norvegicus
2.8.2.14 p-chloromercuribenzoate
-
 Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.8.2.14 0.008
-
 3'-phosphoadenylylsulfate
-
 Rattus norvegicus
2.8.2.14 0.05
-
 taurolithocholate
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.8.2.14 cytosol
-
 Rattus norvegicus 5829
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.8.2.14 Mg2+
-
 Rattus norvegicus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.8.2.14 130000
-
 gel filtration Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.8.2.14 3'-phosphoadenylyl sulfate + taurolithocholate Rattus norvegicus
-
 adenosine 3',5'-bisphosphate + taurolithocholate sulfate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.8.2.14 Rattus norvegicus
-
 rat
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.8.2.14 partial Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.8.2.14 kidney
-
 Rattus norvegicus
-
2.8.2.14 liver
-
 Rattus norvegicus
-
2.8.2.14 additional information not detectable in brain, lung, heart, spleen, intestinal mucosa or red blood cells Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.8.2.14 3'-phosphoadenylyl sulfate + taurolithocholate
-
 Rattus norvegicus adenosine 3',5'-bisphosphate + taurolithocholate sulfate
-
 ?
2.8.2.14 3'-phosphoadenylyl-sulfate + lithocholate
-
 Rattus norvegicus adenosine 3',5'-bisphosphate + lithocholate 3-sulfate
-
 ?
2.8.2.14 additional information rate of sulfation is higher with conjugated bile salts than with unconjugated Rattus norvegicus ?
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.8.2.14 6.5
-
-
 Rattus norvegicus

pI Value

EC Number Organism Comment pI Value Maximum pI Value
2.8.2.14 Rattus norvegicus isoelectric focusing electrophoresis, method originally described by Svensson, maintained at 0°C
-
 5.3