Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Picton, R.; Eggo, M.C.; Merrill, G.A.; Langman, M.J.S.; Singh, S.
    Mucosal protection against sulphide: Importance of the enzyme rhodanese (2002), Gut, 50, 201-205.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.8.1.1 H2S at concentrations above 30 mM Bos taurus
2.8.1.1 H2S at concentrations above 30 mM Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.8.1.1 8.8
-
 H2S 20°C, pH 9.2 Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.8.1.1 thiosulfate + cyanide Homo sapiens
-
 sulfite + thiocyanate
-
 ?
2.8.1.1 thiosulfate + cyanide Bos taurus
-
 sulfite + thiocyanate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.8.1.1 Bos taurus
-
-
-
2.8.1.1 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.8.1.1 colon right and left Homo sapiens
-
2.8.1.1 esophagus
-
 Homo sapiens
-
2.8.1.1 rectum
-
 Homo sapiens
-
2.8.1.1 small intestine
-
 Homo sapiens
-
2.8.1.1 stomach
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.8.1.1 0.015
-
 with H2S as substrate Homo sapiens
2.8.1.1 0.047
-
 oesophagus Homo sapiens
2.8.1.1 0.128
-
 stomach Homo sapiens
2.8.1.1 0.158
-
 small intestine Homo sapiens
2.8.1.1 0.246
-
 left colon Homo sapiens
2.8.1.1 0.254
-
 rectum Homo sapiens
2.8.1.1 0.292
-
 right colon Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.8.1.1 H2S + cyanide
-
 Homo sapiens thiocyanate
-
 ?
2.8.1.1 H2S + cyanide
-
 Bos taurus thiocyanate
-
 ?
2.8.1.1 thiosulfate + cyanide
-
 Homo sapiens sulfite + thiocyanate
-
 ?
2.8.1.1 thiosulfate + cyanide
-
 Bos taurus sulfite + thiocyanate
-
 ?