Literature summary extracted from

Chulavatnatol, M.; Atkinson, D.E.
Phosphoenolpyruvate synthetase from Escherichia coli. Effects of adenylate energy charge and modifier concentrations (1973), J. Biol. Chem., 248, 2712-2715.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.7.9.2	2-oxoglutarate	-	Escherichia coli
2.7.9.2	3-phosphoglyceraldehyde	weak	Escherichia coli
2.7.9.2	ADP	-	Escherichia coli
2.7.9.2	ADP-glucose	weak	Escherichia coli
2.7.9.2	AMP	-	Escherichia coli
2.7.9.2	malate	-	Escherichia coli
2.7.9.2	oxalacetate	-	Escherichia coli
2.7.9.2	phosphoenolpyruvate	competitive to ATP	Escherichia coli

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.7.9.2	Escherichia coli	-	B	-
2.7.9.2	Escherichia coli B / ATCC 11303	-	B	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.7.9.2	ATP + pyruvate + H2O	-	Escherichia coli	AMP + phosphoenolpyruvate + phosphate	-	?
2.7.9.2	ATP + pyruvate + H2O	-	Escherichia coli B / ATCC 11303	AMP + phosphoenolpyruvate + phosphate	-	?

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Release 2023.1 (January 2023)