Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Chirgadze, N.Y.; Briggs, S.L.; McAllister, K.A.; Fischl, A.S.; Zhao, G.
    Crystal structure of Streptococcus pneumoniae acyl carrier protein synthase: an essential enzyme in bacterial fatty acid biosynthesis (2000), EMBO J., 19, 5281-5287.
    View publication on PubMedView publication on EuropePMC

Application

EC Number Application Comment Organism
2.7.8.7 medicine enzyme plays an important role in bacterial fatty acid and lipid biosynthesis, making it an attractive target for therapeutic intervention, drug design by identifying inhibitors with potential antibacterial activity Streptomyces pneumoniae

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.8.7 sequenced Streptomyces pneumoniae

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
2.7.8.7
-
Streptomyces pneumoniae

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.8.7 CoA + apo-[acyl-carrier protein] Streptomyces pneumoniae transfer of acyl fatty acid intermediates during biosynthesis of fatty acids and lipids in the cell adenosine 3',5'-bisphosphate + holo-[acyl-carrier protein]
-
r

Organism

EC Number Organism UniProt Comment Textmining
2.7.8.7 Streptomyces pneumoniae
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.8.7 CoA + apo-[acyl-carrier protein]
-
Streptomyces pneumoniae adenosine 3',5'-bisphosphate + holo-[acyl-carrier protein]
-
r
2.7.8.7 CoA + apo-[acyl-carrier protein] transfer of acyl fatty acid intermediates during biosynthesis of fatty acids and lipids in the cell Streptomyces pneumoniae adenosine 3',5'-bisphosphate + holo-[acyl-carrier protein]
-
r

Subunits

EC Number Subunits Comment Organism
2.7.8.7 trimer
-
Streptomyces pneumoniae

Synonyms

EC Number Synonyms Comment Organism
2.7.8.7 AcpS
-
Streptomyces pneumoniae