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Literature summary extracted from

  • Stuible, H.P.; Meier, S.; Wagner, C.; Hannappel, E.; Schweizer, E.
    A novel phosphopantetheine:protein transferase activating yeast mitochondrial acyl carrier protein (1998), J. Biol. Chem., 273, 22334-22339.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.8.7 open reading frame YPL148C is the potential mitochondrial PPTase gene, expressed in Escherichia coli and Saccharomyces cerevisiae Saccharomyces cerevisiae

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.8.7 cytoplasm
-
 Saccharomyces cerevisiae 5737
-
2.7.8.7 mitochondrion isoenzyme, mutational loss of mitochondrial ACP has no effect on bulk cellular fatty acid synthesis Saccharomyces cerevisiae 5739
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.8.7 20320
-
 mitochondrial isoenzyme, calculated from open reading frame Saccharomyces cerevisiae
2.7.8.7 21000
-
 mitochondrial isoenzyme, SDS-PAGE Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.8.7 CoA + apo-[acyl-carrier protein] Saccharomyces cerevisiae
-
 adenosine 3',5'-bisphosphate + holo-[acyl-carrier protein]
-
 r

Organism

EC Number Organism UniProt Comment Textmining
2.7.8.7 Saccharomyces cerevisiae Q12036 yeast
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.8.7 CoA + apo-[acyl-carrier protein]
-
 Saccharomyces cerevisiae adenosine 3',5'-bisphosphate + holo-[acyl-carrier protein]
-
 r

Synonyms

EC Number Synonyms Comment Organism
2.7.8.7 cytoplasmic type I FAS multienzyme
-
 Saccharomyces cerevisiae
2.7.8.7 mitochondrial type II fatty acid synthase
-
 Saccharomyces cerevisiae
2.7.8.7 PPTase
-
 Saccharomyces cerevisiae

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.8.7 4'-phosphopantetheine prosthetic group Saccharomyces cerevisiae