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Literature summary extracted from
- Cellular and enzymic synthesis of sphingomyelin (1982), Biochemistry, 21, 2753-2759.
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 2.7.8.3 | plasma membrane | - |
Rattus norvegicus | 5886 | - |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 2.7.8.3 | cytidine diphosphate choline + N-acyl-threo-trans-sphingosine | Mesocricetus auratus | - |
CMP + sphingomyelin | - |
? |  |
| 2.7.8.3 | cytidine diphosphate choline + N-acyl-threo-trans-sphingosine | Rattus norvegicus | in vivo the proximal donor of the phosphocholine moiety of sphingomyelin is not CDPcholine but most probably phosphatidylcholine | CMP + sphingomyelin | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 2.7.8.3 | Mesocricetus auratus | - |
hamster, BHK 21 baby hamster kidney cells, ATCC CCL10 | - |
| 2.7.8.3 | Rattus norvegicus | - |
rat | - |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 2.7.8.3 | kidney | - |
Rattus norvegicus | - |
| 2.7.8.3 | kidney | BHK 21 baby hamster kidney cells, ATCC CCL10 | Mesocricetus auratus | - |
| 2.7.8.3 | liver | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 2.7.8.3 | cytidine diphosphate choline + N-acetyl-DL-threo-trans-sphingosine | - |
Rattus norvegicus | CMP + sphingomyelin | - |
? | |
| 2.7.8.3 | cytidine diphosphate choline + N-acetyl-DL-threo-trans-sphingosine | - |
Mesocricetus auratus | CMP + sphingomyelin | - |
? | |
| 2.7.8.3 | cytidine diphosphate choline + N-acyl-threo-trans-sphingosine | - |
Mesocricetus auratus | CMP + sphingomyelin | - |
? | |
| 2.7.8.3 | cytidine diphosphate choline + N-acyl-threo-trans-sphingosine | in vivo the proximal donor of the phosphocholine moiety of sphingomyelin is not CDPcholine but most probably phosphatidylcholine | Rattus norvegicus | CMP + sphingomyelin | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 2.7.8.3 | phosphatidylcholine:ceramide phosphocholinetransferase | - |
Rattus norvegicus |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 2.7.8.3 | 7 | 7.5 | - |
Rattus norvegicus |
| 2.7.8.3 | 7 | 7.5 | - |
Mesocricetus auratus |
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