Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Marggraf, W.D.; Anderer, F.A.
    Alternative pathways in the biosynthesis of sphingomyelin and the role of phosphatidylcholine, CDPcholine and phosphorylcholine as precursors (1974), Hoppe-Seyler's Z. Physiol. Chem., 355, 803-810.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.8.3 cytidine diphosphate choline + N-acyl-threo-trans-sphingosine Mus musculus sphingomyelin is synthesized predominantly via direct transfer of the phosphorylcholine group from phosphatidylcholine, synthesis of sphingomyelin by the action of CDPcholine:ceramide cholinephosphotransferase occurs only to an extent of 2% in vivo CMP + sphingomyelin
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.8.3 Mus musculus
-
 mouse
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.8.3 fibroblast
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.8.3 cytidine diphosphate choline + N-acetyl-DL-threo-trans-sphingosine
-
 Mus musculus CMP + sphingomyelin
-
 ?
2.7.8.3 cytidine diphosphate choline + N-acyl-threo-trans-sphingosine sphingomyelin is synthesized predominantly via direct transfer of the phosphorylcholine group from phosphatidylcholine, synthesis of sphingomyelin by the action of CDPcholine:ceramide cholinephosphotransferase occurs only to an extent of 2% in vivo Mus musculus CMP + sphingomyelin
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.8.3 CDPcholine:ceramide cholinephosphotransferase
-
 Mus musculus