Literature summary extracted from

Haft, R.F.; Wessels, M.R.; Mebane, M.F.; Conaty, N.; Rubens, C.E.
Characterization of cpsF and its product CMP-N-acetylneuraminic acid synthetase, a group B streptococcal enzyme that can function in K1 capsular polysaccharide biosynthesis in Escherichia coli (1996), Mol. Microbiol., 19, 555-563.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
2.7.7.43	expression in Escherichia coli, enzyme can function in K1 capsular polysaccharide biosynthesis in Escherichia coli	Streptococcus sp.

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
2.7.7.43	CTP + N-acylneuraminate	Streptococcus sp.	the enzyme is involved in synthesis of capsular polysaccharide, the recombinant enzyme can function in K1 capsular polysaccharide biosynthesis in Escherichia coli	diphosphate + CMP-N-acylneuraminate	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.7.7.43	Streptococcus sp.	-	group B	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.7.7.43	CTP + N-acylneuraminate	-	Streptococcus sp.	diphosphate + CMP-N-acylneuraminate	-	?
2.7.7.43	CTP + N-acylneuraminate	the enzyme is involved in synthesis of capsular polysaccharide, the recombinant enzyme can function in K1 capsular polysaccharide biosynthesis in Escherichia coli	Streptococcus sp.	diphosphate + CMP-N-acylneuraminate	-	?

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Release 2023.1 (January 2023)