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Literature summary extracted from

  • Vionnet, J.; Concepcion, N.; Warner, T.; Zapata, G.; Hanover, J.; Vann, W.F.
    Purification of CMP-N-acetylneuraminic acid synthetase from bovine anterior pituitary glands (1999), Glycobiology, 9, 481-487.
    View publication on PubMed

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.7.43 52000
-
 3 * 52000, SDS-PAGE Bos taurus
2.7.7.43 158000
-
 gel filtration Bos taurus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.7.43 CTP + N-acylneuraminate Bos taurus the product of the reaction CMP-N-acylneuraminate is the substrate for the sialylation of glycoconjugates by sialyltransferases diphosphate + CMP-N-acylneuraminate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.7.43 Bos taurus
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
2.7.7.43 additional information no carbohydrates can be detected Bos taurus

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.7.43
-
 Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.7.43 anterior pituitary gland
-
 Bos taurus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.7.7.43 18.25
-
-
 Bos taurus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.43 CTP + N-acylneuraminate
-
 Bos taurus diphosphate + CMP-N-acylneuraminate
-
 ?
2.7.7.43 CTP + N-acylneuraminate the product of the reaction CMP-N-acylneuraminate is the substrate for the sialylation of glycoconjugates by sialyltransferases Bos taurus diphosphate + CMP-N-acylneuraminate
-
 ?

Subunits

EC Number Subunits Comment Organism
2.7.7.43 trimer 3 * 52000, SDS-PAGE Bos taurus

pI Value

EC Number Organism Comment pI Value Maximum pI Value
2.7.7.43 Bos taurus isoelectric focusing 5.9 5.6