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Literature summary extracted from

  • Kishi, K.; Yuasa, T.; Minami, A.; Yamada, M.; Hagi, A.; Hayashi, H.; Kemp, B.E.; Witters, L.A.; Ebina, Y.
    AMP-activated protein kinase is activated by the stimulations of G(q)-coupled receptors (2000), Biochem. Biophys. Res. Commun., 276, 16-22.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.11.31 5'-AMP
-
 Cricetulus griseus
2.7.11.31 5-amino-4-imidazolecarboxamide ribonucleoside
-
 Cricetulus griseus

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.31 Cricetulus griseus
-
 chinese hamster, cell line CHO-G4myc
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.11.31 ovary
-
 Cricetulus griseus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.31 additional information enzyme functions as a metabolic sensor that monitors cellular AMP and ATP levels Cricetulus griseus ?
-
 ?

Subunits

EC Number Subunits Comment Organism
2.7.11.31 heterotrimer
-
 Cricetulus griseus
2.7.11.31 More heterotrimeric serine/threonine kinase consists of a catalytic alpha-subunit and 2 regulatory subunits beta and gamma, each subunit exists as multiple isoforms, alpha1, alpha2, beta1, beta2, gamma1, gamma2 and gamma3, giving 12 different possible combinantions of holoenzyme with different tissue distribution and subcellular localization Cricetulus griseus