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Literature summary extracted from

  • Woods, A.; Cheung, P.C.; Smith, F.C.; Davison, M.D.; Scott, J.; Beri, R.K.; Carling, D.
    Characterization of AMP-activated protein kinase beta and gamma subunits. Assembly of the heterotrimeric complex in vitro (1996), J. Biol. Chem., 271, 10282-10290.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.11.31 5'-AMP
-
 Rattus norvegicus

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.11.31 sequence analysis of cDNA clones encoding the subunits Rattus norvegicus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.11.31 30000
-
 beta-subunit, predicted protein sequence Rattus norvegicus
2.7.11.31 36000
-
 1 * 63000 * ? + 1 * 38000 + 1 * 36000, alpha, beta, gamma, SDS-PAGE Rattus norvegicus
2.7.11.31 38000
-
 1 * 63000 * ? + 1 * 38000 + 1 * 36000, alpha, beta, gamma, SDS-PAGE Rattus norvegicus
2.7.11.31 63000
-
 1 * 63000 * ? + 1 * 38000 + 1 * 36000, alpha, beta, gamma, SDS-PAGE Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.31 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.11.31 partial Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.11.31 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.31 ATP + [hydroxymethylglutaryl-CoA reductase (NADPH)]
-
 Rattus norvegicus ADP + [hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
2.7.11.31 heterotrimer 1 * 63000 * ? + 1 * 38000 + 1 * 36000, alpha, beta, gamma, SDS-PAGE Rattus norvegicus