EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
2.7.11.31 | 5'-AMP | - |
Homo sapiens | |
2.7.11.31 | 5-amino-4-imidazolecarboxamide ribotide | - |
Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.11.31 | Homo sapiens | - |
human | - |
2.7.11.31 | Homo sapiens | - |
IDH4, IMr90 and WI38 fibroblasts | - |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.7.11.31 | fibroblast | - |
Homo sapiens | - |
2.7.11.31 | IDH4 cell | - |
Homo sapiens | - |
2.7.11.31 | IMR-90 cell | - |
Homo sapiens | - |
2.7.11.31 | WI-38 cell | - |
Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.11.31 | ATP + RNA-binding protein HUR | inhibits the protein by phosphorylation | Homo sapiens | ADP + ? | - |
? | |
2.7.11.31 | additional information | conditions that elevate the AMP:ATP ratio in cells, such as growth factor depletion, hypoglycemia, ischemia in heart muscle, exercise in skeletal muscle, as well as treatment with arsenite, azide, oxidative agents and the pharmacological agent AICAR, which mimics the effect of AMP can cause activation of AMPK | Homo sapiens | ? | - |
? |