EC Number | Cloned (Comment) | Organism |
---|---|---|
1.21.99.3 | screening of neonatal skin cDNA library, DNA sequence determination and analysis, isozyme type III, an in-frame TGA codon encodes a selenocysteine residue, functional translation in Xenopus laevis oocytes, catalytis properties of recombinant and native enzyme are identical | Rattus norvegicus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.21.99.3 | aurothioglucose | no inhibition, isozyme type III | Rattus norvegicus | |
1.21.99.3 | additional information | no inhibition of 5-deiodinase activity by propylthiouracil | Rattus norvegicus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.21.99.3 | Rattus norvegicus | P49897 | selenoprotein | - |
1.21.99.3 | Rattus norvegicus | P49897 | isozyme type III | - |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.21.99.3 | skin | - |
Rattus norvegicus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.21.99.3 | 3,3',5'-triiodo-L-thyronine + AH2 | no activity | Rattus norvegicus | 3,3'-diiodo-L-thyronine + iodide + A + H+ | - |
? | |
1.21.99.3 | 3,3',5-triiodo-L-thyronine + AH2 | best substrate | Rattus norvegicus | 3,3'-diiodo-L-thyronine + iodide + A + H+ | hormonally inactive | ? | |
1.21.99.3 | 3,3',5-triiodo-L-thyronine + AH2 | isozyme type III | Rattus norvegicus | 3,3'-diiodo-L-thyronine + iodide + A + H+ | hormonally inactive | ? | |
1.21.99.3 | L-thyroxine + AH2 | preferred substrate | Rattus norvegicus | 3,3',5'-triiodo-L-thyronine + iodide + A + H+ | hormonally inactive | ? | |
1.21.99.3 | L-thyroxine + AH2 | isozyme type III | Rattus norvegicus | 3,3',5'-triiodo-L-thyronine + iodide + A + H+ | hormonally inactive | ? | |
1.21.99.3 | L-thyroxine + AH2 | 5-deiodinase activity | Rattus norvegicus | 3,3',5'-triiodo-L-thyronine + iodide + A + H+ | hormonally inactive | ? | |
1.21.99.3 | L-thyroxine + AH2 | no activity | Rattus norvegicus | 3,3',5-triiodo-L-thyronine + iodide + A + H+ | - |
? |