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Literature summary extracted from

  • Nicholson, D.W.; Ali, A.; Vaillancourt, J.P.; Calaycay, J.R.; Mumford, R.A.; Zamboni, R.J.; Ford-Hutchinson, A.W.
    Purification to homogeneity and the N-terminal sequence of human leukotriene C4 synthase: a homodimeric glutathione S-transferase composed of 18-kDa subunits (1993), Proc. Natl. Acad. Sci. USA, 90, 2015-2019.
    View publication on PubMedView publication on EuropePMC

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
4.4.1.20 microsome
-
 Homo sapiens
-
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.4.1.20 39200
-
 gel filtration Homo sapiens
4.4.1.20 180000
-
 2 * 180000, SDS-PAGE Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
4.4.1.20 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.4.1.20
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.4.1.20 HL-60 cell monocytic leukemia cell line Homo sapiens
-
4.4.1.20 lung
-
 Homo sapiens
-
4.4.1.20 monocyte
-
 Homo sapiens
-
4.4.1.20 THP-1 cell monocytic leukemia cell line Homo sapiens
-
4.4.1.20 U-937 cell monocytic leukemia cell line Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.4.1.20 4.135
-
-
 Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.4.1.20 leukotriene A4 + glutathione
-
 Homo sapiens leukotriene C4 + H2O
-
 ?

Subunits

EC Number Subunits Comment Organism
4.4.1.20 dimer 2 * 180000, SDS-PAGE Homo sapiens