Literature summary extracted from

Christmas, P.; Weber, B.M.; McKee, M.; Brown, D.; Soberman, R.J.
Membrane localization and topology of leukotriene C4 synthase (2002), J. Biol. Chem., 277, 28902-28908.

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
4.4.1.20	endoplasmic reticulum	the active site of leukotriene A4 synthase is localized in the lumen of the endoplasmic reticulum	Homo sapiens	5783	-
4.4.1.20	membrane	-	Homo sapiens	16020	-
4.4.1.20	microsome	-	Homo sapiens	-	-
4.4.1.20	nuclear envelope	the active site of leukotriene A4 synthase is localized in the lumen of the nucear envelope and endoplasmic reticulum	Homo sapiens	5635	-
4.4.1.20	nuclear outer membrane	-	Homo sapiens	5640	-

Organism

EC Number	Organism	UniProt	Comment	Textmining
4.4.1.20	Homo sapiens	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4.4.1.20	leukotriene A4 + glutathione	-	Homo sapiens	leukotriene C4 + H2O	-	?

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Release 2023.1 (January 2023)