BRENDA - Enzyme Database

Partial purification of ethanolaminephosphotransferase from rat brain microsomes [published erratum appears in Biochim Biophys Acta 1987 Oct 17;921(3):625]

Vecchini, A.; Roberti, R.; Freysz, L.; Binaglia, L.; Biochim. Biophys. Acta 918, 40-47 (1987)

Data extracted from this reference:

Activating Compound
EC Number
Activating Compound
Commentary
Organism
Structure
2.7.8.1
lysophosphatidylcholine
increases activity
Rattus norvegicus
2.7.8.1
phosphatidylcholine
increases activity
Rattus norvegicus
2.7.8.1
phosphatidylserine
increases activity
Rattus norvegicus
General Stability
EC Number
General Stability
Organism
2.7.8.1
glycerol, diacylglycerol, phosphatidylcholine or lysophosphatidylcholine stabilizes
Rattus norvegicus
Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
2.7.8.1
cholesterol
-
Rattus norvegicus
2.7.8.1
lysophosphatidylserine
-
Rattus norvegicus
2.7.8.1
myristic acid
-
Rattus norvegicus
2.7.8.1
phosphatidic acid
-
Rattus norvegicus
2.7.8.1
phosphatidylethanolamine
-
Rattus norvegicus
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
2.7.8.1
microsome
-
Rattus norvegicus
-
-
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
2.7.8.1
Rattus norvegicus
-
-
-
Purification (Commentary)
EC Number
Commentary
Organism
2.7.8.1
partial
Rattus norvegicus
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
2.7.8.1
brain
-
Rattus norvegicus
-
Specific Activity [micromol/min/mg]
EC Number
Specific Activity Minimum [Ámol/min/mg]
Specific Activity Maximum [Ámol/min/mg]
Commentary
Organism
2.7.8.1
0.0133
-
37░C, pH 8.2
Rattus norvegicus
Storage Stability
EC Number
Storage Stability
Organism
2.7.8.1
-18░C, solubilized enzyme is stable for 3 weeks
Rattus norvegicus
2.7.8.1
4░C, solubilized enzyme is stable for 5 days
Rattus norvegicus
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.7.8.1
CDP-ethanolamine + 1,2-diacylglycerol
-
644406
Rattus norvegicus
CMP + a phosphatidylethanolamine
-
644406
Rattus norvegicus
-
Activating Compound (protein specific)
EC Number
Activating Compound
Commentary
Organism
Structure
2.7.8.1
lysophosphatidylcholine
increases activity
Rattus norvegicus
2.7.8.1
phosphatidylcholine
increases activity
Rattus norvegicus
2.7.8.1
phosphatidylserine
increases activity
Rattus norvegicus
General Stability (protein specific)
EC Number
General Stability
Organism
2.7.8.1
glycerol, diacylglycerol, phosphatidylcholine or lysophosphatidylcholine stabilizes
Rattus norvegicus
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
2.7.8.1
cholesterol
-
Rattus norvegicus
2.7.8.1
lysophosphatidylserine
-
Rattus norvegicus
2.7.8.1
myristic acid
-
Rattus norvegicus
2.7.8.1
phosphatidic acid
-
Rattus norvegicus
2.7.8.1
phosphatidylethanolamine
-
Rattus norvegicus
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
2.7.8.1
microsome
-
Rattus norvegicus
-
-
Purification (Commentary) (protein specific)
EC Number
Commentary
Organism
2.7.8.1
partial
Rattus norvegicus
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
2.7.8.1
brain
-
Rattus norvegicus
-
Specific Activity [micromol/min/mg] (protein specific)
EC Number
Specific Activity Minimum [Ámol/min/mg]
Specific Activity Maximum [Ámol/min/mg]
Commentary
Organism
2.7.8.1
0.0133
-
37░C, pH 8.2
Rattus norvegicus
Storage Stability (protein specific)
EC Number
Storage Stability
Organism
2.7.8.1
-18░C, solubilized enzyme is stable for 3 weeks
Rattus norvegicus
2.7.8.1
4░C, solubilized enzyme is stable for 5 days
Rattus norvegicus
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.7.8.1
CDP-ethanolamine + 1,2-diacylglycerol
-
644406
Rattus norvegicus
CMP + a phosphatidylethanolamine
-
644406
Rattus norvegicus
-