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Literature summary extracted from

  • McMurray, W.C.; Jarvis, E.C.
    Purification and properties of phosphatidylglycerophosphate synthetase from mammalian liver mitochondria (1978), Can. J. Biochem., 56, 414-419.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.8.5 phosphatidylethanolamine stimulates, no stimulation by other diacylglycerophosphatides or lysophosphatides Sus scrofa

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.8.5 Cd2+ strong inhibition at concentrations above 0.5 mM in presence of Mg2+ Sus scrofa
2.7.8.5 Co2+ Mn2+ or Co2+ stimulates at lower concentration, inhibition at higher concentration Sus scrofa
2.7.8.5 Cu2+ strong inhibition at concentrations above 0.5 mM in presence of Mg2+ Sus scrofa
2.7.8.5 Hg2+ strong inhibition at concentrations above 0.5 mM in presence of Mg2+ Sus scrofa
2.7.8.5 Mg2+ Mn2+ or Co2+ stimulates at lower concentration, inhibition at higher concentration Sus scrofa
2.7.8.5 Zn2+ strong inhibition at concentrations above 0.5 mM in presence of Mg2+ Sus scrofa

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.8.5 mitochondrion membrane Rattus norvegicus 5739
-
2.7.8.5 mitochondrion membrane Sus scrofa 5739
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.8.5 Ba2+ cation requirement is relatively nonspecific, Mg2+, Ba2+ or Ca2+ provides maximal activation in the 10 mM range, Mn2+ or Co2+ stimulates at lower concentration, inhibition at higher concentration Sus scrofa
2.7.8.5 Ca2+ cation requirement is relatively nonspecific, Mg2+, Ba2+ or Ca2+ provide maximal activation in the 10 mM range, Mn2+ or Co2+ stimulates at lower concentration, inhibition at higher concentration Sus scrofa
2.7.8.5 Co2+ cation requirement is relatively nonspecific, Mg2+, Ba2+ or Ca2+ provides maximal activation in the 10 mM range, Mn2+ or Co2+ stimulates at lower concentration, inhibition at higher concentration Sus scrofa
2.7.8.5 Mg2+ cation requirement is relatively nonspecific, Mg2+, Ba2+ or Ca2+ provide maximal activation in the 10 mM range, Mn2+ or Co2+ stimulates at lower concentration, inhibition at higher concentration Sus scrofa
2.7.8.5 Mn2+ cation requirement is relatively nonspecific, Mg2+, Ba2+ or Ca2+ provides maximal activation in the 10 mM range, Mn2+ or Co2+ stimulates at lower concentration, inhibition at higher concentration Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
2.7.8.5 Rattus norvegicus
-
-
-
2.7.8.5 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.8.5 liver
-
 Sus scrofa
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.7.8.5 additional information
-
-
 Sus scrofa

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.8.5 CDP-diacylglycerol + sn-glycero-3-phosphate
-
 Rattus norvegicus CMP + phosphatidylglycerophosphate
-
 ?
2.7.8.5 CDP-diacylglycerol + sn-glycero-3-phosphate
-
 Sus scrofa CMP + phosphatidylglycerophosphate
-
 ?

Temperature Range [°C]

EC Number Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
2.7.8.5 37
-
 assay at Sus scrofa