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Literature summary extracted from

  • Sazontova, T.G.; Matskevich, A.A.; Arkhipenko, Y.V.
    Calpains: physiological and pathophysiological significance (1999), Pathophysiology, 6, 91-102.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.22.52 Al3+ inactivates enzyme from smooth muscle at millimolar concentrations of Ca2+, calpain 1 and 2 Rattus norvegicus
3.4.22.52 calpastatin 1 calpain 1 is under constant inhibiting effect of active calpastatin 1 Rattus norvegicus
3.4.22.52 Pb2+
-
 Rattus norvegicus
3.4.22.53 Al3+ inactivation at millimolar concentration of Ca2+ Rattus norvegicus
3.4.22.53 caplastatin 2
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.22.52 cytoplasm
-
 Rattus norvegicus 5737
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.4.22.53 Al3+ millimolar concentrations of Al3+ activate at at submillimolar concentrations of Ca2+ Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
3.4.22.52 Rattus norvegicus
-
-
-
3.4.22.53 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.22.52 heart
-
 Rattus norvegicus
-
3.4.22.52 red muscle
-
 Rattus norvegicus
-
3.4.22.52 smooth muscle
-
 Rattus norvegicus
-
3.4.22.53 heart
-
 Rattus norvegicus
-
3.4.22.53 smooth muscle
-
 Rattus norvegicus
-