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Literature summary extracted from

  • Ishinaga, M.; Kato, M.; Kito, M.
    Effects of phospholipids on soluble phosphatidylserine synthetase of Escherichia coli (1974), FEBS Lett., 49, 201-202.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.8.8 cardiolipin activates. The enzyme is completely desensitized by treatment for 5 min at 40°C against the effect of cadiolipin without loss of activity Escherichia coli
2.7.8.8 phosphatidylethanolamine slightly activates. The enzyme is completely desensitized by treatment for 5 min at 40°C against the effect of phosphatidylethanolamine without loss of activity Escherichia coli

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.8.8 0.085
-
 L-Ser pH 7.2, 37°C, membrane-bound enzyme Escherichia coli

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.8.8 CDP-diacylglycerol + L-serine Escherichia coli the enzyme participates in the biosynthesis of phosphatidylethanolamine CMP + 3-O-sn-phosphatidyl-L-serine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.8.8 Escherichia coli
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.8.8 CDP-1,2-dicaproyl-DL-glycerol + L-Ser
-
 Escherichia coli CMP + 3-O-sn-1,2-dicaproylphosphatidylserine
-
 ?
2.7.8.8 CDP-1,2-dipalmitoyl-L-glycerol + L-Ser
-
 Escherichia coli CMP + 1,2-dipalmitoylphosphatidylserine
-
 ?
2.7.8.8 CDP-diacylglycerol + L-Ser
-
 Escherichia coli CMP + 3-O-sn-phosphatidyl-L-serine
-
 ?
2.7.8.8 CDP-diacylglycerol + L-serine the enzyme participates in the biosynthesis of phosphatidylethanolamine Escherichia coli CMP + 3-O-sn-phosphatidyl-L-serine
-
 ?