Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Chou, J.Y.; Singer, M.F.
    Deoxyadenosine diphosphate as a substrate and inhibitor of polynucleotide phosphorylase of Micrococcus luteus. II. Inhibition of the initiation of adenosine diphosphate polymerization by deoxyadenosine diphosphate (1971), J. Biol. Chem., 246, 7497-7504.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.7.8 dADP competitive inhibition of de novo polymerization of ADP by primer-independent form I and primer-dependent form T Micrococcus luteus

Organism

EC Number Organism UniProt Comment Textmining
2.7.7.8 Micrococcus luteus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.8 poly(A) + ADP
-
 Micrococcus luteus poly(A)+1 + phosphate
-
 r
2.7.7.8 RNAn + a nucleoside diphosphate
-
 Micrococcus luteus RNAn+1 + phosphate
-
 ?

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.7.7.8 0.003 0.004 dADP pH 9.0, 37°C, inhibition of ADP polymerization Micrococcus luteus