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Literature summary extracted from

  • Yomo, T.; Hatanaka, T.; Yamamoto, H.; Yamamoto, K.; Shima, Y.; Ko-Mitamura, E.P.; Urabe, I.
    Kinetic equation for template-dependent polymerase reactions and its application to Thermus thermophilus DNA polymerase (1998), J. Ferment. Bioeng., 86, 379-384.
No PubMed abstract available

Application

EC Number Application Comment Organism
2.7.7.7 biotechnology thermostable polymerase used in PCR Thermus thermophilus
2.7.7.7 molecular biology thermostable polymerase used in PCR Thermus thermophilus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.7.7 deoxynucleoside triphosphate work as competitive inhibitors depending on their incorporation sites, A-incorporation is strongly inhibited by dTTP and dGTP, T-incorporation is inhibited by dATP, G-and C-incorporation sites are less sensitive to competitive inhibition Thermus thermophilus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.7.7 deoxynucleoside triphosphate + DNAn Thermus thermophilus
-
 diphosphate + DNAn+1
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.7.7 Thermus thermophilus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.7 deoxynucleoside triphosphate + DNAn
-
 Thermus thermophilus diphosphate + DNAn+1
-
 ?