Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Sethi, V.S.
    Structure and function of DNA-dependent RNA-polymerase (1971), Prog. Biophys. Mol. Biol., 23, 67-101.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.7.6 1-[2-[3-(4-Chloro-3-trifluoromethylphenyl)ureido]-4-trifluoromethyl phenoxy]-4,5-dichlorobenzene sulfonic acid
-
 Escherichia coli
2.7.7.6 actinomycin
-
 Escherichia coli
2.7.7.6 amanitin
-
 Escherichia coli
2.7.7.6 aureolic acid
-
 Escherichia coli
2.7.7.6 chromomycin
-
 Escherichia coli
2.7.7.6 Cinerubin B
-
 Escherichia coli
2.7.7.6 Cordycepin triphosphate
-
 Escherichia coli
2.7.7.6 daunomycin
-
 Escherichia coli
2.7.7.6 echinomycin
-
 Escherichia coli
2.7.7.6 Eruticulomycin A
-
 Escherichia coli
2.7.7.6 Ethidium bromide
-
 Escherichia coli
2.7.7.6 Exotoxin of Bacillus thuringiensis
-
 Escherichia coli
2.7.7.6 heparin
-
 Escherichia coli
2.7.7.6 Isoquinocyclin
-
 Escherichia coli
2.7.7.6 Nogalamycin
-
 Escherichia coli
2.7.7.6 Olivomycin
-
 Escherichia coli
2.7.7.6 proflavin sulfate
-
 Escherichia coli
2.7.7.6 rifampicin
-
 Escherichia coli
2.7.7.6 Streptolydigin
-
 Escherichia coli
2.7.7.6 streptovaricin
-
 Escherichia coli

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.7.6 40000
-
 beta‘x,beta,sigma,alpha, x * 160000 + x * 145000 + x * 85000 + x * 40000, SDS-PAGE Escherichia coli
2.7.7.6 85000
-
 beta‘x,beta,sigma,alpha, x * 160000 + x * 145000 + x * 85000 + x * 40000, SDS-PAGE Escherichia coli
2.7.7.6 145000
-
 beta‘x,beta,sigma,alpha, x * 160000 + x * 145000 + x * 85000 + x * 40000, SDS-PAGE Escherichia coli
2.7.7.6 160000
-
 beta‘x,beta,sigma,alpha, x * 160000 + x * 145000 + x * 85000 + x * 40000, SDS-PAGE Escherichia coli

Organism

EC Number Organism UniProt Comment Textmining
2.7.7.6 Escherichia coli
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.7.6
-
 Escherichia coli

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.6 nucleoside triphosphate + RNAn the enzyme requires DNA as template Escherichia coli diphosphate + RNAn+1
-
 ?

Subunits

EC Number Subunits Comment Organism
2.7.7.6 ? beta‘x,beta,sigma,alpha, x * 160000 + x * 145000 + x * 85000 + x * 40000, SDS-PAGE Escherichia coli
2.7.7.6 More dimer-monomer formation is reversible and the equilibrium depends on the ionic strength of the medium. At high ionic strength the enzyme dissociates to a monomeric form Escherichia coli