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Literature summary extracted from

  • Goodin, M.M.; Schlagnhaufer, B.; Weir, T.; Romaine, C.P.
    Characterization of an RNA-dependent RNA polymerase activity associated with La France isometric virus (1997), J. Virol., 71, 2264-2269.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.7.48 additional information the enzyme is resistant to inhibitors of DNA-dependent RNA polymerase activity: actinomycin D, alpha-amanitin and rifampin La France isometric virus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.7.48 Mg2+ maximal activity in presence of La France isometric virus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.7.48 nucleoside triphosphate + RNAn La France isometric virus the enzyme is probably a transcriptase engaged in the synthesis of ssRNA transcripts corresponding to each of the virion-associated dsRNAs diphosphate + RNAn+1
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 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.7.48 La France isometric virus
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 Agaricus bisporus infected with
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Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.7.48
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 La France isometric virus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.7.48 additional information tissue of Agaricus bisporus La France isometric virus
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.48 nucleoside triphosphate + RNAn
-
 La France isometric virus diphosphate + RNAn+1
-
 ?
2.7.7.48 nucleoside triphosphate + RNAn the enzyme is probably a transcriptase engaged in the synthesis of ssRNA transcripts corresponding to each of the virion-associated dsRNAs La France isometric virus diphosphate + RNAn+1
-
 ?