Literature summary extracted from

Lazarus, L.H.; Itin, A.
Activity of Foot-and-mouth disease virus RNA-dependent RNA polymerase in vitro: inhibition by polyamines and poly(amino acid)s (1973), Arch. Biochem. Biophys., 156, 154-160.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.7.7.48	cadaverine	-	Foot-and-mouth disease virus
2.7.7.48	Polyarginine	strong	Foot-and-mouth disease virus
2.7.7.48	polylysine	strong	Foot-and-mouth disease virus
2.7.7.48	Polyornithine	strong	Foot-and-mouth disease virus
2.7.7.48	putrescine	-	Foot-and-mouth disease virus
2.7.7.48	spermine	-	Foot-and-mouth disease virus

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.7.7.48	Foot-and-mouth disease virus	-	BHK cells infected with	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.7.7.48	nucleoside triphosphate + RNAn	-	Foot-and-mouth disease virus	diphosphate + RNAn+1	-	?

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Release 2023.1 (January 2023)