Literature summary extracted from

Ohki, K.; Hori, K.
Replication of viral nucleic acids. II. Inhibition of Q replicase by sulfhydryl-blocking reagents (1972), Biochim. Biophys. Acta, 281, 233-243.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.7.7.48	HgCl2	inhibition is reversed by incubation with an excess amount of dithiothreitol and 2-mercaptoethanol	Qubevirus durum
2.7.7.48	PCMB	inhibition is reversed by incubation with an excess amount of dithiothreitol and 2-mercaptoethanol. PCMB-inhibited enzyme is unable to synthesize RNA, but still maintains template-binding ability	Qubevirus durum

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.7.7.48	Qubevirus durum	-	Escherichia coli infected with	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.7.7.48	nucleoside triphosphate + RNAn	-	Qubevirus durum	diphosphate + RNAn+1	-	?

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Release 2023.1 (January 2023)