Literature summary extracted from

Wu, L.; Niemeyer, B.; Colley, N.; Socolich, M.; Zuker, C.S.
Regulation of PLC-mediated signaling in vivo by CDP-diacylglycerol synthase (1995), Nature, 373, 216-222.

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
2.7.7.41	CTP + phosphatidate	Drosophila sp. (in: flies)	the enzyme is required for the regeneration of the signalling molecule phosphatidylinositol-4,5-diphosphate from phosphatidic acid. A photoreceptor cell-specific isoform is a key regulator of phototransduction, a G-protein-coupled signalling cascade mediated by phospholipase C	diphosphate + CDPdiacylglycerol	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.7.7.41	Drosophila sp. (in: flies)	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.7.7.41	eye	-	Drosophila sp. (in: flies)	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.7.7.41	CTP + phosphatidate	-	Drosophila sp. (in: flies)	diphosphate + CDPdiacylglycerol	-	?
2.7.7.41	CTP + phosphatidate	the enzyme is required for the regeneration of the signalling molecule phosphatidylinositol-4,5-diphosphate from phosphatidic acid. A photoreceptor cell-specific isoform is a key regulator of phototransduction, a G-protein-coupled signalling cascade mediated by phospholipase C	Drosophila sp. (in: flies)	diphosphate + CDPdiacylglycerol	-	?

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)