BRENDA - Enzyme Database

Studies on the formation by rat brain preparations of CDP-diglyceride from CTP and phosphatidic acids of varying fatty acid compositions

Bishop, H.H.; Strickland, K.P.; Can. J. Biochem. 54, 249-260 (1976)

Data extracted from this reference:

Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
2.7.7.41
microsome
mainly located in microsomal fraction
Rattus norvegicus
-
-
Metals/Ions
EC Number
Metals/Ions
Commentary
Organism
Structure
2.7.7.41
Mg2+
optimal concentration is 60 mM
Rattus norvegicus
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
2.7.7.41
Rattus norvegicus
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
2.7.7.41
brain
-
Rattus norvegicus
-
2.7.7.41
heart
-
Rattus norvegicus
-
2.7.7.41
kidney
-
Rattus norvegicus
-
2.7.7.41
liver
-
Rattus norvegicus
-
2.7.7.41
lung
-
Rattus norvegicus
-
2.7.7.41
small intestine
-
Rattus norvegicus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.7.7.41
CTP + 1,2-diarachidonoyl phosphatidic acid
-
643312
Rattus norvegicus
diphosphate + CDP-1,2-diarachidonoylglycerol
-
-
-
?
2.7.7.41
CTP + 1,2-dicaproyl phosphatidic acid
-
643312
Rattus norvegicus
diphosphate + CDP-1,2-dicaproylglycerol
-
-
-
?
2.7.7.41
CTP + 1,2-dioleoyl phosphatidic acid
-
643312
Rattus norvegicus
diphosphate + CDP-dioleoylglycerol
-
-
-
?
2.7.7.41
CTP + 1,2-dipalmitoyl phosphatidic acid
-
643312
Rattus norvegicus
diphosphate + CDP-dipalmitoylglycerol
-
-
-
-
2.7.7.41
CTP + 1,2-distearoyl phosphatidic acid
-
643312
Rattus norvegicus
diphosphate + CDP-1,2-distearoylglycerol
-
-
-
?
2.7.7.41
CTP + 1-arachidonoyl-2-stearoyl phosphatidic acid
-
643312
Rattus norvegicus
diphosphate + CDP-1-arachidonoyl-2-stearoylglycerol
-
-
-
?
2.7.7.41
CTP + 1-oleoyl-2-stearoyl phosphatidic acid
-
643312
Rattus norvegicus
diphosphate + CDP-1-oleoyl-2-stearoylglycerol
-
-
-
?
2.7.7.41
CTP + 1-palmitoyl-2-oleoyl phosphatidic acid
-
643312
Rattus norvegicus
diphosphate + CDP-1-palmitoyl-2-oleoylglycerol
-
-
-
?
2.7.7.41
CTP + 1-stearoyl-2-arachidonoyl phosphatidic acid
-
643312
Rattus norvegicus
diphosphate + CDP-1-stearoyl-2-arachidonoylglycerol
-
-
-
?
2.7.7.41
CTP + 1-stearoyl-2-oleoyl phosphatidic acid
-
643312
Rattus norvegicus
diphosphate + CDP-1-stearoyl-2-oleoylglycerol
-
-
-
?
2.7.7.41
CTP + phosphatidate
reaction with 1,2-dioleoylphosphatidic acid. Varying the fatty acid composition in the phosphatidic acids added exogenously gives the following order of decreasing activity: 1-stearoyl-2-oleoylphosphatidic acid, 1-oleoyl-2-stearoylphosphatidic acid, 1,2-dioleoylphosphatidic acid, 1-palmitoyl-2-oleoylphosphatidic acid, 1-stearoyl-2-arachidonoylphosphatidic acid, 1-arachidonoyl-2-stearoylphosphatidic acid, 1,2-diarachidonoylphosphatidic acid, 1,2-dicaproylphosphatidic acid, 1,2-dipalmitoylphosphatidic acid, 1,2-distearoylphosphatidic acid
643312
Rattus norvegicus
diphosphate + CDPdiacylglycerol
-
-
-
?
pH Optimum
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
2.7.7.41
6.8
-
reaction with 1,2-dioleoylphosphatidic acid
Rattus norvegicus
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
2.7.7.41
microsome
mainly located in microsomal fraction
Rattus norvegicus
-
-
Metals/Ions (protein specific)
EC Number
Metals/Ions
Commentary
Organism
Structure
2.7.7.41
Mg2+
optimal concentration is 60 mM
Rattus norvegicus
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
2.7.7.41
brain
-
Rattus norvegicus
-
2.7.7.41
heart
-
Rattus norvegicus
-
2.7.7.41
kidney
-
Rattus norvegicus
-
2.7.7.41
liver
-
Rattus norvegicus
-
2.7.7.41
lung
-
Rattus norvegicus
-
2.7.7.41
small intestine
-
Rattus norvegicus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.7.7.41
CTP + 1,2-diarachidonoyl phosphatidic acid
-
643312
Rattus norvegicus
diphosphate + CDP-1,2-diarachidonoylglycerol
-
-
-
?
2.7.7.41
CTP + 1,2-dicaproyl phosphatidic acid
-
643312
Rattus norvegicus
diphosphate + CDP-1,2-dicaproylglycerol
-
-
-
?
2.7.7.41
CTP + 1,2-dioleoyl phosphatidic acid
-
643312
Rattus norvegicus
diphosphate + CDP-dioleoylglycerol
-
-
-
?
2.7.7.41
CTP + 1,2-dipalmitoyl phosphatidic acid
-
643312
Rattus norvegicus
diphosphate + CDP-dipalmitoylglycerol
-
-
-
-
2.7.7.41
CTP + 1,2-distearoyl phosphatidic acid
-
643312
Rattus norvegicus
diphosphate + CDP-1,2-distearoylglycerol
-
-
-
?
2.7.7.41
CTP + 1-arachidonoyl-2-stearoyl phosphatidic acid
-
643312
Rattus norvegicus
diphosphate + CDP-1-arachidonoyl-2-stearoylglycerol
-
-
-
?
2.7.7.41
CTP + 1-oleoyl-2-stearoyl phosphatidic acid
-
643312
Rattus norvegicus
diphosphate + CDP-1-oleoyl-2-stearoylglycerol
-
-
-
?
2.7.7.41
CTP + 1-palmitoyl-2-oleoyl phosphatidic acid
-
643312
Rattus norvegicus
diphosphate + CDP-1-palmitoyl-2-oleoylglycerol
-
-
-
?
2.7.7.41
CTP + 1-stearoyl-2-arachidonoyl phosphatidic acid
-
643312
Rattus norvegicus
diphosphate + CDP-1-stearoyl-2-arachidonoylglycerol
-
-
-
?
2.7.7.41
CTP + 1-stearoyl-2-oleoyl phosphatidic acid
-
643312
Rattus norvegicus
diphosphate + CDP-1-stearoyl-2-oleoylglycerol
-
-
-
?
2.7.7.41
CTP + phosphatidate
reaction with 1,2-dioleoylphosphatidic acid. Varying the fatty acid composition in the phosphatidic acids added exogenously gives the following order of decreasing activity: 1-stearoyl-2-oleoylphosphatidic acid, 1-oleoyl-2-stearoylphosphatidic acid, 1,2-dioleoylphosphatidic acid, 1-palmitoyl-2-oleoylphosphatidic acid, 1-stearoyl-2-arachidonoylphosphatidic acid, 1-arachidonoyl-2-stearoylphosphatidic acid, 1,2-diarachidonoylphosphatidic acid, 1,2-dicaproylphosphatidic acid, 1,2-dipalmitoylphosphatidic acid, 1,2-distearoylphosphatidic acid
643312
Rattus norvegicus
diphosphate + CDPdiacylglycerol
-
-
-
?
pH Optimum (protein specific)
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
2.7.7.41
6.8
-
reaction with 1,2-dioleoylphosphatidic acid
Rattus norvegicus