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Literature summary extracted from

  • Bishop, H.H.; Strickland, K.P.
    Studies on the formation by rat brain preparations of CDP-diglyceride from CTP and phosphatidic acids of varying fatty acid compositions (1976), Can. J. Biochem., 54, 249-260.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.7.41 microsome mainly located in microsomal fraction Rattus norvegicus
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-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.7.41 Mg2+ optimal concentration is 60 mM Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
2.7.7.41 Rattus norvegicus
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-
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.7.41 brain
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 Rattus norvegicus
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2.7.7.41 heart
-
 Rattus norvegicus
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2.7.7.41 kidney
-
 Rattus norvegicus
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2.7.7.41 liver
-
 Rattus norvegicus
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2.7.7.41 lung
-
 Rattus norvegicus
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2.7.7.41 small intestine
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 Rattus norvegicus
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.41 CTP + 1,2-diarachidonoyl phosphatidic acid
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 Rattus norvegicus diphosphate + CDP-1,2-diarachidonoylglycerol
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 ?
2.7.7.41 CTP + 1,2-dicaproyl phosphatidic acid
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 Rattus norvegicus diphosphate + CDP-1,2-dicaproylglycerol
-
 ?
2.7.7.41 CTP + 1,2-dioleoyl phosphatidic acid
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 Rattus norvegicus diphosphate + CDP-dioleoylglycerol
-
 ?
2.7.7.41 CTP + 1,2-dipalmitoyl phosphatidic acid
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 Rattus norvegicus diphosphate + CDP-dipalmitoylglycerol
-
 ?
2.7.7.41 CTP + 1,2-distearoyl phosphatidic acid
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 Rattus norvegicus diphosphate + CDP-1,2-distearoylglycerol
-
 ?
2.7.7.41 CTP + 1-arachidonoyl-2-stearoyl phosphatidic acid
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 Rattus norvegicus diphosphate + CDP-1-arachidonoyl-2-stearoylglycerol
-
 ?
2.7.7.41 CTP + 1-oleoyl-2-stearoyl phosphatidic acid
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 Rattus norvegicus diphosphate + CDP-1-oleoyl-2-stearoylglycerol
-
 ?
2.7.7.41 CTP + 1-palmitoyl-2-oleoyl phosphatidic acid
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 Rattus norvegicus diphosphate + CDP-1-palmitoyl-2-oleoylglycerol
-
 ?
2.7.7.41 CTP + 1-stearoyl-2-arachidonoyl phosphatidic acid
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 Rattus norvegicus diphosphate + CDP-1-stearoyl-2-arachidonoylglycerol
-
 ?
2.7.7.41 CTP + 1-stearoyl-2-oleoyl phosphatidic acid
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 Rattus norvegicus diphosphate + CDP-1-stearoyl-2-oleoylglycerol
-
 ?
2.7.7.41 CTP + phosphatidate reaction with 1,2-dioleoylphosphatidic acid. Varying the fatty acid composition in the phosphatidic acids added exogenously gives the following order of decreasing activity: 1-stearoyl-2-oleoylphosphatidic acid, 1-oleoyl-2-stearoylphosphatidic acid, 1,2-dioleoylphosphatidic acid, 1-palmitoyl-2-oleoylphosphatidic acid, 1-stearoyl-2-arachidonoylphosphatidic acid, 1-arachidonoyl-2-stearoylphosphatidic acid, 1,2-diarachidonoylphosphatidic acid, 1,2-dicaproylphosphatidic acid, 1,2-dipalmitoylphosphatidic acid, 1,2-distearoylphosphatidic acid Rattus norvegicus diphosphate + CDPdiacylglycerol
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 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.7.7.41 6.8
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 reaction with 1,2-dioleoylphosphatidic acid Rattus norvegicus