BRENDA - Enzyme Database

The biosynthesis of cytidine diphosphate diglyceride by embryonic chick brain

Petzold, G.L.; Agranoff, B.W.; J. Biol. Chem. 242, 1187-1191 (1967)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
2.7.7.41
deoxycholate
partial inhibition
Gallus gallus
2.7.7.41
Mg2+
in presence of Mn2+
Gallus gallus
2.7.7.41
palmitoyl-CoA
inhibits incorporation of CTP into CDP-diglyceride in presence or absence of added phosphatidic acid
Gallus gallus
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
2.7.7.41
particle-bound
-
Gallus gallus
-
-
Metals/Ions
EC Number
Metals/Ions
Commentary
Organism
Structure
2.7.7.41
Mn2+
maximal activity at 18 mM
Gallus gallus
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
2.7.7.41
Gallus gallus
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
2.7.7.41
brain
embryonic
Gallus gallus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.7.7.41
CTP + phosphatidate
didecanoyl phosphatidic acid is the most active of the synthetic phosphatidic acids tested, lysophosphatidic acid is a poor substrate
643299
Gallus gallus
diphosphate + CDPdiacylglycerol
-
-
-
?
pH Optimum
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
2.7.7.41
7
-
-
Gallus gallus
pH Range
EC Number
pH Minimum
pH Maximum
Commentary
Organism
2.7.7.41
5.8
7.6
pH 5.8: 60% of maximal activity, pH 7.6: about 55% of maximal activity
Gallus gallus
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
2.7.7.41
deoxycholate
partial inhibition
Gallus gallus
2.7.7.41
Mg2+
in presence of Mn2+
Gallus gallus
2.7.7.41
palmitoyl-CoA
inhibits incorporation of CTP into CDP-diglyceride in presence or absence of added phosphatidic acid
Gallus gallus
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
2.7.7.41
particle-bound
-
Gallus gallus
-
-
Metals/Ions (protein specific)
EC Number
Metals/Ions
Commentary
Organism
Structure
2.7.7.41
Mn2+
maximal activity at 18 mM
Gallus gallus
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
2.7.7.41
brain
embryonic
Gallus gallus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.7.7.41
CTP + phosphatidate
didecanoyl phosphatidic acid is the most active of the synthetic phosphatidic acids tested, lysophosphatidic acid is a poor substrate
643299
Gallus gallus
diphosphate + CDPdiacylglycerol
-
-
-
?
pH Optimum (protein specific)
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
2.7.7.41
7
-
-
Gallus gallus
pH Range (protein specific)
EC Number
pH Minimum
pH Maximum
Commentary
Organism
2.7.7.41
5.8
7.6
pH 5.8: 60% of maximal activity, pH 7.6: about 55% of maximal activity
Gallus gallus