BRENDA - Enzyme Database

Bovine brain microsomal CDP-diacylglycerol synthetase: solubilization and properties

Lin, C.H.; Lin, J.; Strickland, K.P.; Biochem. Int. 25, 299-306 (1991)

Data extracted from this reference:

Activating Compound
EC Number
Activating Compound
Commentary
Organism
Structure
2.7.7.41
CHAPS
maximal activity at 0.5%
Bos taurus
2.7.7.41
phosphatidylcholine
the solubilized but not the microsomal enzyme is activated
Bos taurus
Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
2.7.7.41
5,5'-dithiobis(2-nitrobenzoic acid)
-
Bos taurus
2.7.7.41
cardiolipin
the solubilized but not the microsomal enzyme is strongly inhibited
Bos taurus
2.7.7.41
CHAPS
at 0.3%
Bos taurus
2.7.7.41
lysophosphatidylcholine
the solubilized but not the microsomal enzyme is strongly inhibited
Bos taurus
2.7.7.41
NEM
-
Bos taurus
2.7.7.41
PCMB
-
Bos taurus
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
2.7.7.41
microsome
-
Bos taurus
-
-
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
2.7.7.41
Bos taurus
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
2.7.7.41
brain
-
Bos taurus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.7.7.41
CTP + phosphatidate
phosphatidic acid from egg lecithin and 1-stearoyl 2-arachidonoyl phosphatidic acid are preferred substrates for the microsomal enzyme
643298
Bos taurus
diphosphate + CDPdiacylglycerol
-
-
-
?
Activating Compound (protein specific)
EC Number
Activating Compound
Commentary
Organism
Structure
2.7.7.41
CHAPS
maximal activity at 0.5%
Bos taurus
2.7.7.41
phosphatidylcholine
the solubilized but not the microsomal enzyme is activated
Bos taurus
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
2.7.7.41
5,5'-dithiobis(2-nitrobenzoic acid)
-
Bos taurus
2.7.7.41
cardiolipin
the solubilized but not the microsomal enzyme is strongly inhibited
Bos taurus
2.7.7.41
CHAPS
at 0.3%
Bos taurus
2.7.7.41
lysophosphatidylcholine
the solubilized but not the microsomal enzyme is strongly inhibited
Bos taurus
2.7.7.41
NEM
-
Bos taurus
2.7.7.41
PCMB
-
Bos taurus
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
2.7.7.41
microsome
-
Bos taurus
-
-
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
2.7.7.41
brain
-
Bos taurus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.7.7.41
CTP + phosphatidate
phosphatidic acid from egg lecithin and 1-stearoyl 2-arachidonoyl phosphatidic acid are preferred substrates for the microsomal enzyme
643298
Bos taurus
diphosphate + CDPdiacylglycerol
-
-
-
?