BRENDA - Enzyme Database

Poly(A) polymerase from Escherichia coli adenylylates the 3'-hydroxyl residue of nucleosides, nucleoside 5'-phosphates and nucleoside(5')oligophospho(5')nucleosides (NpnN)

Sillero, M.A.; Socorro, S.; Baptista, M.J.; Del Valle, M.; De Diego, A.; Sillero, A.; Eur. J. Biochem. 268, 3605-3611 (2001)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
2.7.7.19
GMP
1 mM, complete inhibition of enzymic reaction with tRNA
Escherichia coli
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
2.7.7.19
Escherichia coli
-
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.7.7.19
ATP + adenosine(5')diphospho(5')adenosine
i.e. AP2A
642991
Escherichia coli
diphosphate + ?
-
-
-
?
2.7.7.19
ATP + adenosine(5')pentaphospho(5')adenosine
i.e. AP5A
642991
Escherichia coli
diphosphate + ?
-
-
-
?
2.7.7.19
ATP + adenosine(5')tetraphospho(5')adenosine
i.e. AP4A
642991
Escherichia coli
diphosphate + ?
-
-
-
?
2.7.7.19
ATP + adenosine(5')triphospho(5')adenosine
i.e. AP3A
642991
Escherichia coli
diphosphate + ?
-
-
-
?
2.7.7.19
ATP + AMP
-
642991
Escherichia coli
diphosphate + ?
-
-
-
?
2.7.7.19
ATP + CMP
-
642991
Escherichia coli
diphosphate + ?
-
-
-
?
2.7.7.19
ATP + CTP
-
642991
Escherichia coli
diphosphate + ?
-
-
-
?
2.7.7.19
ATP + dGTP
-
642991
Escherichia coli
diphosphate + ?
-
-
-
?
2.7.7.19
ATP + GDP
-
642991
Escherichia coli
diphosphate + ?
-
-
-
?
2.7.7.19
ATP + GTP
-
642991
Escherichia coli
diphosphate + ?
-
-
-
?
2.7.7.19
ATP + guanosine
-
642991
Escherichia coli
diphosphate + ?
-
-
-
?
2.7.7.19
ATP + guanosine(5')diphospho(5')guanosine
i.e. GP2G
642991
Escherichia coli
diphosphate + ?
-
-
-
?
2.7.7.19
ATP + guanosine(5')pentaphospho(5')guanosine
i.e. GP5G
642991
Escherichia coli
diphosphate + ?
-
-
-
?
2.7.7.19
ATP + guanosine(5')tetraphospho(5')guanosine
i.e. GP4G
642991
Escherichia coli
diphosphate + ?
-
-
-
?
2.7.7.19
ATP + guanosine(5')triphospho(5')guanosine
i.e. GP3G
642991
Escherichia coli
diphosphate + ?
-
-
-
?
2.7.7.19
ATP + IMP
-
642991
Escherichia coli
diphosphate + ?
-
-
-
?
2.7.7.19
ATP + XTP
-
642991
Escherichia coli
diphosphate + ?
-
-
-
?
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
2.7.7.19
GMP
1 mM, complete inhibition of enzymic reaction with tRNA
Escherichia coli
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.7.7.19
ATP + adenosine(5')diphospho(5')adenosine
i.e. AP2A
642991
Escherichia coli
diphosphate + ?
-
-
-
?
2.7.7.19
ATP + adenosine(5')pentaphospho(5')adenosine
i.e. AP5A
642991
Escherichia coli
diphosphate + ?
-
-
-
?
2.7.7.19
ATP + adenosine(5')tetraphospho(5')adenosine
i.e. AP4A
642991
Escherichia coli
diphosphate + ?
-
-
-
?
2.7.7.19
ATP + adenosine(5')triphospho(5')adenosine
i.e. AP3A
642991
Escherichia coli
diphosphate + ?
-
-
-
?
2.7.7.19
ATP + AMP
-
642991
Escherichia coli
diphosphate + ?
-
-
-
?
2.7.7.19
ATP + CMP
-
642991
Escherichia coli
diphosphate + ?
-
-
-
?
2.7.7.19
ATP + CTP
-
642991
Escherichia coli
diphosphate + ?
-
-
-
?
2.7.7.19
ATP + dGTP
-
642991
Escherichia coli
diphosphate + ?
-
-
-
?
2.7.7.19
ATP + GDP
-
642991
Escherichia coli
diphosphate + ?
-
-
-
?
2.7.7.19
ATP + GTP
-
642991
Escherichia coli
diphosphate + ?
-
-
-
?
2.7.7.19
ATP + guanosine
-
642991
Escherichia coli
diphosphate + ?
-
-
-
?
2.7.7.19
ATP + guanosine(5')diphospho(5')guanosine
i.e. GP2G
642991
Escherichia coli
diphosphate + ?
-
-
-
?
2.7.7.19
ATP + guanosine(5')pentaphospho(5')guanosine
i.e. GP5G
642991
Escherichia coli
diphosphate + ?
-
-
-
?
2.7.7.19
ATP + guanosine(5')tetraphospho(5')guanosine
i.e. GP4G
642991
Escherichia coli
diphosphate + ?
-
-
-
?
2.7.7.19
ATP + guanosine(5')triphospho(5')guanosine
i.e. GP3G
642991
Escherichia coli
diphosphate + ?
-
-
-
?
2.7.7.19
ATP + IMP
-
642991
Escherichia coli
diphosphate + ?
-
-
-
?
2.7.7.19
ATP + XTP
-
642991
Escherichia coli
diphosphate + ?
-
-
-
?