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Literature summary extracted from

  • Friesen, J.A.; Liu, M.F.; Kent, C.
    Cloning and characterization of a lipid-activated CTP:phosphocholine cytidylyltransferase from Caenorhabditis elegans: identification of a 21-residue segment critical for lipid activation (2001), Biochim. Biophys. Acta, 1533, 86-98.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.7.15 wild-type and truncated forms Caenorhabditis elegans

Protein Variants

EC Number Protein Variants Comment Organism
2.7.7.15 additional information mutants truncated after amino acids 225 or 245 are active in the absence of lipids and not further activated in the presence of lipids, mutants truncated after amino acids 226, 281 or 319 are activated by lipid similar to wild-type enzyme Caenorhabditis elegans

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.7.15 additional information
-
 additional information
-
 Caenorhabditis elegans

Organism

EC Number Organism UniProt Comment Textmining
2.7.7.15 Caenorhabditis elegans
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.7.15 wild-type and truncated forms Caenorhabditis elegans

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.7.7.15 11
-
-
 Caenorhabditis elegans

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.15 CTP + choline phosphate
-
 Caenorhabditis elegans diphosphate + CDPcholine
-
 ?

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
2.7.7.15 additional information
-
 additional information
-
 Caenorhabditis elegans