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Literature summary extracted from

  • Cornell, R.B.; Kalmar, G.B.; Kay, R.J.; Johnson, M.A.; Sanghera, J.S.; Pelech, S.L.
    Functions of the C-terminal domain of CTP:phosphocholine cytidylyltransferase. Effects of C-terminal deletions on enzyme activity, intracellular localization and phosphorylation potential (1995), Biochem. J., 310, 699-708.
No PubMed abstract available

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.7.15
-
 Rattus norvegicus

Protein Variants

EC Number Protein Variants Comment Organism
2.7.7.15 H89A
-
 Rattus norvegicus
2.7.7.15 H89G
-
 Rattus norvegicus
2.7.7.15 H89N
-
 Rattus norvegicus
2.7.7.15 H89Q
-
 Rattus norvegicus
2.7.7.15 H92A
-
 Rattus norvegicus
2.7.7.15 H92G
-
 Rattus norvegicus
2.7.7.15 H92N
-
 Rattus norvegicus
2.7.7.15 H92Q
-
 Rattus norvegicus
2.7.7.15 additional information deletion of 55 C-terminal amino acids has no effect on enzyme activity, deletion of 139 C-terminal amino acids results in 90% decrease of enzyme activity Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.7.15 cytosol
-
 Rattus norvegicus 5829
-
2.7.7.15 membrane
-
 Rattus norvegicus 16020
-
2.7.7.15 microsome
-
 Rattus norvegicus
-
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.7.15 41700
-
 SDS-PAGE Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
2.7.7.15 Rattus norvegicus
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
2.7.7.15 phosphoprotein phosphorylation is restricted to the C-terminal 52 amino acids and occurs on multiple sites, 0.2 mol phosphate per mol enzyme Rattus norvegicus

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.7.15
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.7.15 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.15 CTP + choline phosphate
-
 Rattus norvegicus diphosphate + CDPcholine
-
 ?