EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
2.7.7.15 | fatty acids | activity slightly enhanced by addition of saturated fatty acids, markedly increased by addition of unsaturated fatty acids regardless of chain length and number of double bonds | Rattus norvegicus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.7.7.15 | CDPcholine | competitive to choline phosphate | Rattus norvegicus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.7.7.15 | 0.3 | - |
choline phosphate | pH 7.4, 37°C | Rattus norvegicus | |
2.7.7.15 | 10 | - |
CTP | pH 7.4, 37°C | Rattus norvegicus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.7.7.15 | cytosol | - |
Rattus norvegicus | 5829 | - |
2.7.7.15 | microsome | - |
Rattus norvegicus | - |
- |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
2.7.7.15 | Mg2+ | required | Rattus norvegicus | |
2.7.7.15 | Mg2+ | 2-20 mM | Rattus norvegicus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.7.15 | CTP + choline phosphate | Rattus norvegicus | rate limiting step in synthesis of phosphatidylcholine | diphosphate + CDPcholine | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.7.15 | Rattus norvegicus | - |
- |
- |
EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
2.7.7.15 | CTP + phosphocholine = diphosphate + CDP-choline | random mechanism | Rattus norvegicus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.7.7.15 | brain | - |
Rattus norvegicus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.7.15 | CTP + choline phosphate | - |
Rattus norvegicus | diphosphate + CDPcholine | - |
? | |
2.7.7.15 | CTP + choline phosphate | rate limiting step in synthesis of phosphatidylcholine | Rattus norvegicus | diphosphate + CDPcholine | - |
? |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
2.7.7.15 | 7 | - |
- |
Rattus norvegicus |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.7.7.15 | 0.09 | - |
CDPcholine | pH 7.4, 37°C | Rattus norvegicus |